ADAR1 (ADAR) (NM_001111) Human Tagged ORF Clone
CAT#: RC207522
- TrueORF®
ADAR (Myc-DDK-tagged)-Human adenosine deaminase, RNA-specific (ADAR), transcript variant 1
ORF Plasmid: tGFP
"NM_001111" in other vectors (6)
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CNY 12,800.00
Cited in 3 publications. |
CNY 300.00
CNY 6,281.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | ADAR1; AGS6; DRADA; DSH; DSRAD; G1P1; IFI-4; IFI4; K88DSRBP; P136 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001111 |
ORF Size | 3678 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001111.5 |
RefSeq Size | 6692 bp |
RefSeq ORF | 3681 bp |
Locus ID | 103 |
UniProt ID | P55265 |
Domains | z-alpha, DSRM, A_deamin |
Protein Families | Druggable Genome |
Protein Pathways | Cytosolic DNA-sensing pathway |
MW | 136 kDa |
Gene Summary | This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010] |
Citations (3)
The use of this cDNA Clones has been cited in the following citations: |
---|
RNA modifications can affect RNase H1-mediated PS-ASO activity
,null,
Molecular Therapy. Nucleic Acids
,PubMed ID 35664704
[ADAR1]
|
The Role of ADAR1 and ADAR2 in the Regulation of miRNA-21 in Idiopathic Pulmonary Fibrosis
,Díaz-Piña, G;Ordoñez-Razo, RM;Montes, E;Páramo, I;Becerril, C;Salgado, A;Santibañez-Salgado, JA;Maldonado, M;Ruiz, V;,
Lung
,PubMed ID 29637273
[ADAR1]
|
PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas.
,null,
Cellular and molecular life sciences : CMLS
,PubMed ID 26047657
[ADAR1]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC207522L1 | Lenti ORF clone of Human adenosine deaminase, RNA-specific (ADAR), transcript variant 1, Myc-DDK-tagged |
CNY 15,200.00 |
|
RC207522L2 | Lenti ORF clone of Human adenosine deaminase, RNA-specific (ADAR), transcript variant 1, mGFP tagged |
CNY 11,500.00 |
|
RC207522L3 | Lenti ORF clone of Human adenosine deaminase, RNA-specific (ADAR), transcript variant 1, Myc-DDK-tagged |
CNY 15,200.00 |
|
RC207522L4 | Lenti ORF clone of Human adenosine deaminase, RNA-specific (ADAR), transcript variant 1, mGFP tagged |
CNY 15,200.00 |
|
RG207522 | ADAR (tGFP-tagged) - Human adenosine deaminase, RNA-specific (ADAR), transcript variant 1 |
CNY 14,400.00 |
|
SC119438 | ADAR (untagged)-Human adenosine deaminase, RNA-specific (ADAR), transcript variant 1 |
CNY 12,816.00 |