MALT1 (NM_173844) Human Tagged Lenti ORF Clone
CAT#: RC204322L2
- LentiORF®
Lenti ORF clone of Human mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 2, mGFP tagged
"NM_173844" in other vectors (6)
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CNY 5,890.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Synonyms | IMD12; MLT; MLT1; PCASP1 |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC204322).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_173844 |
ORF Size | 2439 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_173844.1 |
RefSeq Size | 4996 bp |
RefSeq ORF | 2442 bp |
Locus ID | 10892 |
UniProt ID | Q9UDY8 |
Protein Families | Druggable Genome, Protease |
Protein Pathways | B cell receptor signaling pathway, T cell receptor signaling pathway |
MW | 90.9 kDa |
Gene Summary | This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204322 | MALT1 (Myc-DDK-tagged)-Human mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 2 |
CNY 5,952.00 |
|
RC204322L1 | Lenti ORF clone of Human mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 2, Myc-DDK-tagged |
CNY 8,352.00 |
|
RC204322L3 | Lenti ORF clone of Human mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204322L4 | Lenti ORF clone of Human mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 2, mGFP tagged |
CNY 8,352.00 |
|
RG204322 | MALT1 (tGFP-tagged) - Human mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 2 |
CNY 7,552.00 |
|
SC108434 | MALT1 (untagged)-Human mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 2 |
CNY 7,220.00 |