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Nrxn1 (NM_020252) Mouse Tagged Lenti ORF Clone
CAT＃: MR226542L4
- LentiORF®
Lenti ORF clone of Nrxn1 (mGFP-tagged) - Mouse neurexin I (Nrxn1), transcript variant 1
"NM_020252" in other vectors (4)
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CNY 13,970.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | mGFP |
| Synonyms | 1700062G21Rik; 9330127H16Rik; A230068P09Rik; mKIAA0578 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR226542).
|
| Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_020252 |
| ORF Size | 4521 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_020252.3, NP_064648.3 |
| RefSeq Size | 9040 bp |
| RefSeq ORF | 4524 bp |
| Locus ID | 18189 |
| UniProt ID | Q9CS84 |
| Gene Summary | This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are synaptic transmembrane receptors that bind endogenous ligands that include neuroligins, dystroglycan, and neurexophilins. Neurexin complexes are required for efficient neurotransmission and are involved in synaptogenesis. In vertebrates, alternate promoter usage results in multiple isoform classes, of which the alpha and beta classes are the best characterized. In humans, allelic variants in this gene are associated with Pitt-Hopkins-like syndrome-2, while deletions have been associated with autism and schizophrenia. Mouse knockouts display decreased spontaneous and evoked vesicle release resulting in impaired synaptic transmission. In addition, knockout mice show altered social approach, reduced social investigation, reduced locomotor activity, and in males, increased aggression. Alternative splicing and promoter usage result in multiple transcript variants. [provided by RefSeq, Nov 2016] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC224615 | Nrxn1 (untagged) - Mouse neurexin I (Nrxn1), transcript variant 1, (10ug) |
CNY 19,290.00 |
|
| MG226542 | Nrxn1 (tGFP-tagged) - Mouse neurexin I (Nrxn1) transcript variant 1, (10ug) |
CNY 13,300.00 |
|
| MR226542 | Nrxn1 (Myc-DDK-tagged) - Mouse neurexin I (Nrxn1), transcript variant 1 |
CNY 10,312.00 |
|
| MR226542L3 | Lenti ORF clone of Nrxn1 (Myc-DDK-tagged) - Mouse neurexin I (Nrxn1), transcript variant 1 |
CNY 13,970.00 |
