Foxn4 (NM_148935) Mouse Tagged Lenti ORF Clone
CAT#: MR223040L4
- LentiORF®
Lenti ORF clone of Foxn4 (mGFP-tagged) - Mouse forkhead box N4 (Foxn4)
"NM_148935" in other vectors (4)
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CNY 6,460.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR223040).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_148935 |
ORF Size | 1563 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_148935.2, NP_683737.2 |
RefSeq Size | 2970 bp |
RefSeq ORF | 1566 bp |
Locus ID | 116810 |
UniProt ID | Q8K3Q3 |
Gene Summary | Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC217504 | Foxn4 (untagged) - Mouse forkhead box N4 (Foxn4), (10ug) |
CNY 6,750.00 |
|
MG223040 | Foxn4 (tGFP-tagged) - Mouse forkhead box N4 (Foxn4), (10ug) |
CNY 5,040.00 |
|
MR223040 | Foxn4 (Myc-DDK-tagged) - Mouse forkhead box N4 (Foxn4) |
CNY 3,880.00 |
|
MR223040L3 | Lenti ORF clone of Foxn4 (Myc-DDK-tagged) - Mouse forkhead box N4 (Foxn4) |
CNY 6,460.00 |