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Foxn4 (NM_148935) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR223040L3V
- LentiORF®
-
Lenti ORF particles, Foxn4 (Myc-DDK-tagged) - Mouse forkhead box N4 (Foxn4), 200ul, >10^7 TU/mL
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CNY 9,785.00
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Specifications
| Product Data | |
| Product Name | Foxn4 (NM_148935) Mouse Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_148935 |
| ORF Size | 1563 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR223040).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_148935.2, NP_683737.2 |
| RefSeq Size | 2970 bp |
| RefSeq ORF | 1566 bp |
| Locus ID | 116810 |
| Gene Summary | Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development.[UniProtKB/Swiss-Prot Function] |
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