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Xrn2 (NM_011917) Mouse Tagged ORF Clone
CAT＃: MR211279
- TrueORF®
Xrn2 (Myc-DDK-tagged) - Mouse 5'-3' exoribonuclease 2 (Xrn2)
ORF Plasmid: tGFP
"NM_011917" in other vectors (4)
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CNY 6,976.00
CNY 8,360.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR211279 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGAGTCCCGGCGTTCTTCCGCTGGCTCAGCCGCAAGTACCCGTCCATCATTGTCAACTGCGTGGAGG AGAAGCCAAAAGAATGCAACGGTGTAAAGATTCCAGTTGATGCCAGTAAACCTAATCCAAATGATGTGGA GTTTGATAATCTGTATTTGGATATGAATGGGATCATCCACCCCTGCACTCATCCTGAAGACAAACCAGCA CCAAAAAATGAAGATGAAATGATGGTTGCAATTTTTGAGTACATTGACAGACTTTTCAATATTGTAAGAC CAAGAAGACTTCTCTACATGGCAATAGATGGGGTGGCACCACGTGCAAAAATGAATCAGCAGCGTTCAAG GAGGTTCAGAGCATCAAAGGAAGGAATGGAAGCAGCAGTTGAGAAGCAGCGAGTCAGAGAGGAAATACTT GCAAAAGGTGGCTTTCTTCCTCCAGAAGAAATAAAAGAAAGATTTGACAGCAACTGTATTACCCCAGGAA CTGAGTTCATGGACAATCTTGCTAAATGCCTTCGCTATTACATAGCTGATCGTTTAAATAATGACCCTGG GTGGAAAAATTTGACAGTTATATTATCTGATGCTAGTGCACCTGGTGAAGGAGAACACAAAATCATGGAT TACATTAGAAGACAAAGAGCCCAGCCTAACCATGACCCAAATACTCATCATTGTTTGTGTGGAGCTGATG CTGATCTAATTATGCTTGGTCTTGCTACACATGAACCTAACTTCACCATAATCAGAGAAGAATTCAAACC AAATAAACCTAAACCATGTGCTCTTTGTAATCAGTTTGGACACGAGGTCAAGGATTGTGAAGGTTTGCCA AGAGAAAAGAAGGGAAAGCATGATGAACTTGCAGATAGTCTTCCTTGTGCAGAAGGGGAGTTTATCTTCC TTCGGCTGAATGTCCTTCGAGAGTATCTGGAAAGAGAACTCACCATGGCCAGCTTACCATTCCCATTTGA TGTGGAGAGGAGCATTGATGACTGGGTGTTCATGTGCTTCTTTGTGGGGAATGATTTCCTTCCTCACTTG CCATCACTAGAGATTAGGGAAGGTGCAATTGATCGTTTGGTTAACATATACAAAAACGTGGTACACAAAA CTGGGGGTTACCTTACAGAAAGTGGTTATGTCAATCTGCAAAGAGTACAGATGATCATGTTAGCAGTTGG TGAAGTTGAGGATAGCATTTTTAAAAAGAGAAAAGATGATGAGGACAGTTTTAGAAGACGACAGAAAGAA AAAAGAAAGAGGATGAAGAGAGATCAACCAGCTTTTACTCCTAGTGGAATATTAACACCTCATGCCTTGG GTTCAAGAAATTCACCAGGTTGTCAAGTAGCCAGTAATCCAAGACAAGCAGCCTATGAAATGAGGATGCA GAGAAACTCTAGTCCTTCAATATCTCCTAATACAAGTTTTGCATCTGATGGCTCCCCATCTCCACTAGGA GGAATTAAGAGAAAAGCAGAAGACAGTGACAGTGAGCCAGAGCCAGAGGATAACGTCAGGTTATGGGAAG CTGGTTGGAAGCAACGATACTACAAGAACAAATTTGATGTAGATGCAGCTGATGAGAAATTCCGACGTAA GGTTGTTCAGTCCTACGTTGAAGGACTGTGCTGGGTTCTTCGCTATTATTACCAGGGCTGTGCTTCCTGG AAGTGGTATTATCCATTCCATTATGCACCATTTGCCTCAGACTTTGAAGGTATTGCAGACATGTCCTCTG AATTTGAAAAGGGCACAAAACCGTTTAAGCCACTGGAACAACTAATGGGGGTTTTCCCAGCTGCAAGTGG TAACTTTCTACCTCCAACATGGCGGAAGCTCATGAGTGACCCTGATTCCAGTATAATTGACTTCTATCCT GAAGATTTTGCTATTGATTTGAATGGGAAGAAATATGCATGGCAAGGTGTTGCTCTATTGCCATTTGTGG ATGAGCGAAGGCTGCGAGCGGCTCTAGAAGAGGTGTACCCAGACCTCACTCCAGAAGAGAACAGGAGAAA TAGTCTTGGAGGTGATGTTTTGTTTGTGGGAAAACTTCATCCACTACGCGACTTCATTTTAGAGCTGTAT CAGACGGGTTCCACAGAGCCAGTTGATGTGCCACCTGAATTGTGTCACGGGATTCAAGGGACGTTTTCTT TGGATGAAGAAGCCATTCTTCCAGACCAAACAGTATGTTCCCCTGTGCCCATGTTGCGGGACCTGACACA GAACACTGCAGTCAGTATTAATTTTAAAGATCCACAGTTTGCTGAAGATTATGTTTTTAAAGCTGCAATG CTTCCAGGAGCAAGAAAGCCAGCAACAGTTCTGAAACCTGGTGACTGGGAAAAATCCAGCAATGGGCGGC AATGGAAACCTCAGCTTGGCTTTAACCGGGACCGGCGGCCTGTTCACCTGGACCAGGCAGCCTTTAGAAC TTTAGGCCATGTTACACCAAGAGGCTCGGGGACGAGTGTTTATACGAACACTGCACTACCACCTGCCAAT TACCAGGGGAACAATTACAGGCCACTGCTGAGAGGTCAAGCTCAGATCCCAAAACTTATGTCAAATATGA GGCCCCAAGATTCCTGGCGAGGCCCTCCTCCTCTTTTCCAGCAGCATAGATTTGAGAGAAGTGTTGGAGC TGAACCTCTACTGCCATGGAACCGGATGATCCAAAACCAAAATGCAGCCTTTCAGCCAAATCAGTACCAG ATGCTAGGAGGACCTGGAGGCTATCCACCCAGACGTGACGATCACCGAGGAGGGAGACAGGGATATCCCA GAGAAGGACGGAAATACCCTTTGCCACCACCCTCGGGAAGATACAGTTGGAAT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR211279 protein sequence
Red=Cloning site Green=Tags(s) MGVPAFFRWLSRKYPSIIVNCVEEKPKECNGVKIPVDASKPNPNDVEFDNLYLDMNGIIHPCTHPEDKPA PKNEDEMMVAIFEYIDRLFNIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEGMEAAVEKQRVREEIL AKGGFLPPEEIKERFDSNCITPGTEFMDNLAKCLRYYIADRLNNDPGWKNLTVILSDASAPGEGEHKIMD YIRRQRAQPNHDPNTHHCLCGADADLIMLGLATHEPNFTIIREEFKPNKPKPCALCNQFGHEVKDCEGLP REKKGKHDELADSLPCAEGEFIFLRLNVLREYLERELTMASLPFPFDVERSIDDWVFMCFFVGNDFLPHL PSLEIREGAIDRLVNIYKNVVHKTGGYLTESGYVNLQRVQMIMLAVGEVEDSIFKKRKDDEDSFRRRQKE KRKRMKRDQPAFTPSGILTPHALGSRNSPGCQVASNPRQAAYEMRMQRNSSPSISPNTSFASDGSPSPLG GIKRKAEDSDSEPEPEDNVRLWEAGWKQRYYKNKFDVDAADEKFRRKVVQSYVEGLCWVLRYYYQGCASW KWYYPFHYAPFASDFEGIADMSSEFEKGTKPFKPLEQLMGVFPAASGNFLPPTWRKLMSDPDSSIIDFYP EDFAIDLNGKKYAWQGVALLPFVDERRLRAALEEVYPDLTPEENRRNSLGGDVLFVGKLHPLRDFILELY QTGSTEPVDVPPELCHGIQGTFSLDEEAILPDQTVCSPVPMLRDLTQNTAVSINFKDPQFAEDYVFKAAM LPGARKPATVLKPGDWEKSSNGRQWKPQLGFNRDRRPVHLDQAAFRTLGHVTPRGSGTSVYTNTALPPAN YQGNNYRPLLRGQAQIPKLMSNMRPQDSWRGPPPLFQQHRFERSVGAEPLLPWNRMIQNQNAAFQPNQYQ MLGGPGGYPPRRDDHRGGRQGYPREGRKYPLPPPSGRYSWN TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_011917 |
| ORF Size | 2856 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_011917.3 |
| RefSeq Size | 3383 bp |
| RefSeq ORF | 2856 bp |
| Locus ID | 24128 |
| UniProt ID | Q9DBR1 |
| MW | 108.7 kDa |
| Gene Summary | Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC202557 | Xrn2 (untagged) - Mouse 5'-3' exoribonuclease 2 (Xrn2), (10ug) |
CNY 6,976.00 |
|
| MG211279 | Xrn2 (tGFP-tagged) - Mouse 5'-3' exoribonuclease 2 (Xrn2) |
CNY 9,220.00 |
|
| MR211279L3 | Lenti ORF clone of Xrn2 (Myc-DDK-tagged) - Mouse 5'-3' exoribonuclease 2 (Xrn2) |
CNY 10,260.00 |
|
| MR211279L4 | Lenti ORF clone of Xrn2 (mGFP-tagged) - Mouse 5'-3' exoribonuclease 2 (Xrn2) |
CNY 10,260.00 |
