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Xrn2 (NM_011917) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211279L3V
- LentiORF®
-
Lenti ORF particles, Xrn2 (Myc-DDK-tagged) - Mouse 5'-3' exoribonuclease 2 (Xrn2), 200ul, >10^7 TU/mL
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CNY 14,630.00
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规格
| Cited in 1 publication. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | Xrn2 (NM_011917) Mouse Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_011917 |
| ORF Size | 2856 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211279).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_011917.2 |
| RefSeq Size | 3383 bp |
| RefSeq ORF | 2856 bp |
| Locus ID | 24128 |
| Gene Summary | Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
XRN2 interactome reveals its synthetic lethal relationship with PARP1 inhibition
,null,
Scientific Reports
,PubMed ID 32859985
[Xrn2]
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