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Xpc (NM_009531) Mouse Tagged ORF Clone
CAT＃: MR211103
- TrueORF®
Xpc (Myc-DDK-tagged) - Mouse xeroderma pigmentosum, complementation group C (Xpc)
ORF Plasmid: tGFP
"NM_009531" in other vectors (4)
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CNY 9,310.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR211103 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCCCAAAGCGCACCGCAGACGGAAGGCGGCGGAAGCGGGGCCAGAAAACCGAGGACAACAAAGTAG CCCGGCACGAGGAGAGCGTTGCGGATGACTTTGAAGATGAGAAGCAGAAACCCCGAAGGAAGAGCTCTTT CCCGAAAGTCTCTCAAGGAAAGAGGAAGAGGGGCTGCAGTGATCCAGGGGACCCCACAAATGGTGCAGCA AAAAAGAAAGTGGCCAAAGCCACTGCTAAATCCAAGAATCTCAAGGTTCTGAAGGAGGAAGCACTCAGCG ACGGGGATGACTTCCGGGACTCACCAGCTGACTGCAAGAAGGCAAAGAAACACCCAAAAAGCAAGGTGGT GGACCAAGGCACTGATGAAGATGACAGTGAGGATGACTGGGAGGAGGTGGAAGAGCTTACTGAACCTGTG CTGGACATGGGAGAAAATTCTGCCACCTCACCGTCTGACATGCCTGTGAAGGCGGTGGAGATTGAAATTG AAACACCACAGCAGGCGAAAGAACGGGAAAGAAGTGAGAAGATAAAGATGGAGTTTGAGACATACCTGCG GAGGATGATGAAGCGTTTCAATAAAGAAGTACAGGAGAACATGCACAAGGTTCACCTGCTGTGCCTGCTG GCCAGTGGCTTCTATCGAAATAGCATCTGCCGACAGCCAGATCTGCTGGCCATTGGCCTCTCCATCATTC CAATTCGCTTTACCAAGGTGCCACTTCAAGATAGGGATGCCTACTACCTTTCAAACCTGGTAAAGTGGTT CATCGGAACCTTCACTGTCAACGCTGACCTTTCAGCCAGCGAGCAGGACGACCTGCAGACCACCTTGGAA AGGAGGATTGCCATTTACTCTGCGAGGGATAATGAAGAGTTGGTCCATATATTTCTTCTGATTCTTCGGG CTCTGCAGCTGCTCACCCGGCTGGTCTTGTCTCTGCAGCCCATTCCACTGAAGTCAGCTGTGACAAAGGG GAGGAAATCTTCCAAGGAGACATCTGTAGAGGGTCCTGGAGGTTCTTCAGAACTCTCTAGTAACAGTCCA GAAAGCCACAACAAACCTACGACCAGCAGGAGAATCAAAGAAGAAGAAACCTTGTCTGAGGGCAGAGGCA AAGCAACCGCCAGGGGGAAGAGAGGCACAGGCACTGCGGGCAGCAGGCAGCGGAGGAAGCCCTCTTGCAG CGAGGGAGAGGAGGCCGAGCAGAAAGTCCAGGGCCGTCCACATGCCCGGAAGCGGCGTGTGGCTGCCAAG GTGTCATACAAAGAGGAGAGTGAGAGCGATGGGGCAGGCAGCGGCTCTGACTTTGAACCGTCCAGTGGGG AGGGCCAGCATTCCTCTGATGAGGATTGTGAGCCTGGCCCTCGCAAGCAGAAGAGGGCCTCAGCTCCTCA GAGGACAAAGGCTGGGTCTAAGAGTGCTTCCAAGACCCAACGCGGAAGCCAGTGTGACCCGTCAAGCTTT CCGGAGGCGTCTTCAAGCTCTTCAGGCTGTAAGAGAGGCAAGAAGGTTTCCAGTGGTGCTGAAGAGATGG CAGATAGGAAACCTGCTGGTGTAGACCAGTGGCTGGAGGTGTACTGTGAGCCACAGGCAAAGTGGGTGTG TGTGGACTGTGTACATGGTGTGGTGGGCCAGCCTGTGGCCTGTTACAAATATGCCACCAAACCCATGACC TATGTTGTAGGCATTGACAGTGATGGCTGGGTCCGAGATGTTACTCAGAGGTATGACCCAGCCTGGATGA CCGCAACCCGCAAGTGCCGGGTTGATGCTGAGTGGTGGGCTGAGACCTTGAGACCCTATCGGAGCCTACT TACGGAGAGGGAGAAGAAGGAAGACCAGGAGTTTCAGGCGAAGCACCTGGACCAGCCTTTGCCCACCTCC ATCAGCACATACAAGAACCACCCTCTGTATGCCCTGAAGCGCCACCTCTTGAAATTCCAGGCTATCTACC CTGAGACAGCTGCGGTGCTCGGGTATTGTCGTGGAGAAGCAGTCTATTCCAGGGATTGCGTGCATACCTT GCACTCCAGGGACACATGGCTGAAGCAAGCAAGAGTGGTGCGGCTTGGAGAAGTGCCCTATAAGATGGTG AAAGGCTTCTCTAACCGTGCCCGGAAAGCCCGGCTCTCGGAGCCCCAGCTGCATGACCACAACGACTTGG GCCTCTATGGTCACTGGCAGACGGAAGAGTATCAGCCTCCTATAGCTGTCGATGGGAAGGTGCCTCGGAA TGAGTTTGGGAACGTGTACCTCTTCCTGCCCAGCATGATGCCCGTCGGCTGTGTCCAGATGACCCTGCCT AACCTGAACCGGGTGGCACGCAAGCTGGGCATCGACTGCGTGCAGGCCATCACTGGCTTCGATTTCCATG GAGGCTATTGCCATCCAGTAACTGATGGCTACATTGTCTGTGAGGAATTCAGAGACGTGCTGCTGGCTGC TTGGGAGAATGAACAGGCCATCATTGAAAAGAAGGAGAAGGAGAAAAAGGAAAAGCGGGCGCTGGGGAAC TGGAAGCTGCTGGTCATAGGACTCCTCATCAGAGAGAGGCTGAAACTCCGCTATGGGGCCAAGAGCGAGG CAGCAGCTCCCCATGCTGCTGGAGGCGGACTCTCTTCTGATGAAGAGGAAGGGACCAGTTCACAAGCAGA AGCAGCCAGAGTCCTGGCTGCCTCCTGGCCACAGAACCGAGAGGATCCAGAACAGAAGTCCGAGTACACT AAGATGACTCGGAAGAGGCGGGCGGCAGAGGCTTCCCACCTCTTTCCGTTTGAGAAGCTG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR211103 protein sequence
Red=Cloning site Green=Tags(s) MAPKRTADGRRRKRGQKTEDNKVARHEESVADDFEDEKQKPRRKSSFPKVSQGKRKRGCSDPGDPTNGAA KKKVAKATAKSKNLKVLKEEALSDGDDFRDSPADCKKAKKHPKSKVVDQGTDEDDSEDDWEEVEELTEPV LDMGENSATSPSDMPVKAVEIEIETPQQAKERERSEKIKMEFETYLRRMMKRFNKEVQENMHKVHLLCLL ASGFYRNSICRQPDLLAIGLSIIPIRFTKVPLQDRDAYYLSNLVKWFIGTFTVNADLSASEQDDLQTTLE RRIAIYSARDNEELVHIFLLILRALQLLTRLVLSLQPIPLKSAVTKGRKSSKETSVEGPGGSSELSSNSP ESHNKPTTSRRIKEEETLSEGRGKATARGKRGTGTAGSRQRRKPSCSEGEEAEQKVQGRPHARKRRVAAK VSYKEESESDGAGSGSDFEPSSGEGQHSSDEDCEPGPRKQKRASAPQRTKAGSKSASKTQRGSQCDPSSF PEASSSSSGCKRGKKVSSGAEEMADRKPAGVDQWLEVYCEPQAKWVCVDCVHGVVGQPVACYKYATKPMT YVVGIDSDGWVRDVTQRYDPAWMTATRKCRVDAEWWAETLRPYRSLLTEREKKEDQEFQAKHLDQPLPTS ISTYKNHPLYALKRHLLKFQAIYPETAAVLGYCRGEAVYSRDCVHTLHSRDTWLKQARVVRLGEVPYKMV KGFSNRARKARLSEPQLHDHNDLGLYGHWQTEEYQPPIAVDGKVPRNEFGNVYLFLPSMMPVGCVQMTLP NLNRVARKLGIDCVQAITGFDFHGGYCHPVTDGYIVCEEFRDVLLAAWENEQAIIEKKEKEKKEKRALGN WKLLVIGLLIRERLKLRYGAKSEAAAPHAAGGGLSSDEEEGTSSQAEAARVLAASWPQNREDPEQKSEYT KMTRKRRAAEASHLFPFEKL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_009531 |
| ORF Size | 2793 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_009531.2, NP_033557.2 |
| RefSeq Size | 3634 bp |
| RefSeq ORF | 2793 bp |
| Locus ID | 22591 |
| UniProt ID | P51612 |
| MW | 104.5 kDa |
| Gene Summary | Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by Rad23b and Rad23a. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC222687 | Xpc (untagged) - Mouse xeroderma pigmentosum, complementation group C (Xpc), (10ug) |
CNY 11,970.00 |
|
| MG211103 | Xpc (tGFP-tagged) - Mouse xeroderma pigmentosum, complementation group C (Xpc) |
CNY 10,260.00 |
|
| MR211103L3 | Lenti ORF clone of Xpc (Myc-DDK-tagged) - Mouse xeroderma pigmentosum, complementation group C (Xpc) |
CNY 11,210.00 |
|
| MR211103L4 | Lenti ORF clone of Xpc (mGFP-tagged) - Mouse xeroderma pigmentosum, complementation group C (Xpc) |
CNY 11,210.00 |
