Xpc (NM_009531) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR211103L4V
- LentiORF®
Lenti ORF particles, Xpc (GFP-tagged) - Mouse xeroderma pigmentosum, complementation group C (Xpc), 200ul, >10^7 TU/mL
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CNY 16,055.00
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Specifications
Product Data | |
Product Name | Xpc (NM_009531) Mouse Tagged ORF Clone Lentiviral Particle |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_009531 |
ORF Size | 2793 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR211103).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009531.2, NP_033557.2 |
RefSeq Size | 3634 bp |
RefSeq ORF | 2793 bp |
Locus ID | 22591 |
Gene Summary | Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by Rad23b and Rad23a. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity.[UniProtKB/Swiss-Prot Function] |
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