Ptprs (BC052462) Mouse Untagged Clone

CAT#: MC224572

Ptprs (untagged) - Mouse protein tyrosine phosphatase, receptor type, S (cDNA clone MGC:63375 IMAGE:6834684), (10ug)



  "BC052462" in other vectors (4)

CNY 19,190.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (2)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms PTP-NU3, PTPsigma
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC052462
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCGCCCACCTGGAGTCCCAGCGTGGTGTCTGTGGTGGGTCCTGTGGGGCTCTTCCTCGTACTGCTGG
CCAGAGGATGCTTGGCTGAAGAACCACCCAGGTTTATCAGAGAGCCCAAGGATCAGATTGGAGTGTCGGG
AGGCGTGGCCTCCTTCGTGTGCCAGGCCACGGGTGATCCTAAGCCACGGGTGACCTGGAACAAGAAGGGC
AAGAAAGTGAACTCACAGCGCTTCGAGACCATTGACTTTGACGAGAGCTCTGGGGCGGTCCTGAGGATCC
AGCCACTTCGGACGCCTCGGGATGAGAACGTGTACGAGTGTGTGGCCCAGAACTCGGTGGGCGAAATCAC
AATTCATGCAAAGCTCACCGTCCTTCGAGAGGACCAGCTGCCTCCTGGCTTCCCCAACATTGACATGGGC
CCCCAGTTGAAGGTTGTAGAGCGCACACGCACAGCCACCATGCTCTGTGCTGCCAGCGGGAACCCGGACC
CTGAGATCACCTGGTTTAAGGACTTCCTGCCTGTGGACCCCAGTGCCAGCAACGGGCGGATCAAGCAGCT
TCGATCAGGTGCCCTGCAGATTGAGAGCAGCGAGGAGACAGACCAGGGCAAGTACGAGTGTGTGGCCACC
AACAGCGCTGGGGTGCGCTACTCATCACCTGCCAACCTCTACGTGCGAGTCCGCCGTGTGGCCCCACGCT
TCTCCATCCTGCCCATGAGCCACGAGATCATGCCCGGTGGGAATGTGAATATCACTTGTGTGGCCGTGGG
CTCACCCATGCCCTACGTGAAATGGATGCAGGGGGCCGAGGACCTGACGCCTGAGGATGACATGCCCGTG
GGTCGGAATGTTCTAGAACTCACGGATGTCAAGGACTCAGCTAACTACACTTGTGTGGCCATGTCCAGCC
TGGGTGTGATCGAGGCCGTGGCCCAGATCACTGTAAAATCTCTCCCCAAAGCCCCTGGGACTCCTGTGGT
GACGGAGAACACTGCCACCAGTATCACTGTCACATGGGACTCGGGCAACCCTGACCCCGTGTCCTACTAC
GTAATTGAGTATAAGTCCAAAAGCCAGGATGGGCCGTATCAGATCAAAGAAGACATCACCACCACGCGCT
ACAGCATCGGAGGCCTGAGCCCCAATTCTGAGTATGAGATCTGGGTGTCAGCTGTCAACTCCATTGGCCA
GGGCCCTCCCAGTGAATCGGTGGTGACCCGCACAGGTGAGCAGGCACCAGCCAGCGCTCCCAGGAATGTT
CAGGCCCGCATGCTCAGCGCCACCACCATGATCGTGCAGTGGGAGGAGCCTGTGGAGCCCAATGGCCTGA
TCCGTGGCTACCGTGTCTACTATACCATGGAGCCGGAACACCCAGTGGGCAACTGGCAGAAACACAATGT
GGACGACAGTCTCCTGACCACTGTGGGCAGCCTGCTGGAAGACGAGACCTACACCGTGCGCGTGCTCGCC
TTCACGTCGGTGGGCGACGGACCACTGTCAGACCCCATCCAGGTCAAGACCCAGCAGGGAGTTCCTGGCC
AGCCCATGAACTTGCGGGCTGAGGCCAAGTCAGAGACCAGCATTGGGCTCTCGTGGAGTGCACCACGACA
GGAGAGTGTCATTAAGTATGAACTGCTCTTCCGGGAGGGCGACCGAGGCCGAGAGGTGGGGCGAACCTTC
GACCCAACCACAGCCTTTGTGGTGGAGGACCTCAAGCCCAATACGGAGTATGCGTTCCGGCTGGCGGCGC
GCTCGCCGCAGGGCCTGGGCGCCTTCACCGCGGTCGTGCGCCAGCGCACGCTGCAGGCCATCTCCCCAAA
GAACTTCAAGGTGAAGATGATCATGAAGACTTCAGTGCTGCTGAGCTGGGAGTTCCCCGACAACTATAAC
TCACCCACACCCTACAAGATTCAGTACAATGGGCTCACCCTGGATGTGGACGGCCGCACGACCAAGAAGC
TGATCACACACCTCAAGCCACACACCTTCTATAATTTCGTGCTCACCAACCGTGGCAGCAGCCTGGGGGG
CCTGCAGCAGACGGTCACTGCCAGGACCGCCTTTAACATGCTCAGTGGCAAGCCTAGCGTCGCCCCGAAG
CCCGACAATGACGGTTTCATCGTGGTCTACCTGCCTGATGGCCAGAGTCCTGTGACCGTGCAGAACTACT
TCATTGTGATGGTCCCACTTCGGAAGTCTCGAGGTGGCCAGTTCCCTGTCCTACTAGGTAGTCCAGAGGA
CATGGATCTGGAGGAGCTCATCCAGGACATCTCCCGGCTGCAGAGGCGCAGCCTGCGCCACTCCAGACAG
CTGGAGGTGCCTCGGCCCTACATCGCCGCTCGATTCTCCATCCTGCCAGCTGTCTTCCATCCTGGGAACC
AGAAGCAATATGGTGGCTTTGACAACAGGGGCTTGGAGCCAGGCCACCGCTATGTCCTCTTTGTGCTTGC
TGTGTTGCAGAAGAATGAGCCTACATTTGCAGCCAGTCCCTTCTCAGACCCCTTCCAGCTGGACAACCCG
GACCCTCAGCCCATTGTGGACGGCGAGGAGGGCCTCATCTGGGTGATTGGGCCTGTGCTGGCCGTGGTCT
TCATCATCTGCATCGTGATTGCCATCCTGCTGTACAAGAACAAACCTGACAGCAAACGCAAGGACTCAGA
GCCCCGCACCAAATGCTTACTGAACAATGCCGACCTTGCCCCCCATCACCCCAAGGACCCTGTGGAAATG
CGACGCATCAACTTCCAGACACCAGGTATGCTCAGCCACCCACCCATCCCCATCACAGACATGGCGGAGC
ACATGGAGAGACTCAAAGCCAACGACAGCCTGAAGCTCTCCCAGGAGTACGAGTCCATTGACCCCGGGCA
GCAATTCACGTGGGAACATTCGAACCTGGAGGCCAACAAGCCCAAGAACCGCTATGCCAACGTCATCGCC
TATGACCACTCACGAGTCATCCTGCAGCCCCTAGAAGGCATCATGGGTAGTGATTACATCAATGCCAACT
ATGTGGACGGCTACCGGCGGCAGAATGCATACATTGCCACGCAGGGGCCCCTGCCTGAGACCTTTGGGGA
CTTCTGGCGGATGGTGTGGGAGCAGCGATCGGCCACTGTGGTCATGATGACGCGACTGGAGGAGAAATCA
CGGATCAAATGTGACCAATACTGGCCTAACCGAGGCACCGAGACATACGGCTTCATCCAGGTCACCCTAC
TAGATACCATGGAGCTGGCTACCTTCTGCGTCAGGACTTTTTCTCTACACAAGAATGGCTCTAGCGAGAA
GCGTGAGGTGCGACATTTCCAGTTCACGGCATGGCCCGACCACGGGGTACCTGAGTACCCCACGCCCTTC
CTGGCATTCCTGCGAAGAGTCAAGACCTGCAACCCGCCTGATGCTGGCCCCATTGTGGTCCACTGCAGCG
CGGGTGTGGGGCGCACTGGCTGCTTCATCGTAATTGACGCCATGCTAGAGCGCATCAAGACAGAGAAGAC
CGTGGATGTGTATGGACATGTGACACTCATGCGGTCGCAGCGCAACTACATGGTGCAGACAGAGGATCAG
TATGGCTTCATCCACGAGGCGCTGCTGGAGGCTGTGGGCTGCGGCAATACCGAGGTCCCTGCTCGCAGCC
TCTACACCTACATCCAGAAGCTGGCCCAGGTGGAGCCTGGCGAGCACGTCACGGGCATGGAGCTTGAGTT
CAAGAGGCTCGCCAGTTCCAAGGCACACACTTCGCGCTTCATCACCGCCAGCCTGCCTTGCAACAAGTTT
AAGAACCGACTGGTGAACATCCTGCCGTACGAGAGCTCGCGTGTCTGCCTGCAGCCCATCCGCGGTGTGG
AGGGCTCTGACTACATCAATGCCAGCTTTATCGACGGCTATAGACAGCAGAAAGCCTACATTGCAACACA
GGGGCCACTGGCAGAGACCACAGAGGACTTCTGGCGAGCTCTGTGGGAGAACAACTCTACTATTGTCGTA
ATGCTCACCAAGCTCCGAGAAATGGGCCGGGAAAAGTGCCACCAGTACTGGCCAGCCGAGCGCTCTGCCC
GCTACCAGTACTTTGTGGTTGACCCGATGGCAGAGTATAACATGCCACAGTACATTCTGCGTGAGTTTAA
GGTCACAGATGCCCGGGATGGCCAGTCCCGGACCGTCCGACAGTTCCAGTTCACGGACTGGCCAGAGCAG
GGTGCACCCAAGTCAGGGGAAGGCTTCATTGACTTCATCGGCCAAGTGCATAAGACCAAGGAGCAGTTTG
GCCAGGACGGACCCATCTCAGTGCACTGCAGCGCCGGAGTGGGCAGGACCGGAGTGTTCATCACCCTGAG
CATCGTGCTTGAGCGGATGCGCTACGAGGGCGTGGTGGACATTTTCCAGACAGTGAAGGTGCTTCGGACC
CAGAGGCCTGCCATGGTGCAGACAGAGGACGAGTACCAGTTCTGCTTCCAGGCGGCTTTGGAATACCTGG
GCAGTTTTGATCATTATGCAACATAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCTGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAG
GTTTAA
Restriction Sites SgfI-MluI     
ACCN BC052462
Insert Size 4506 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq BC052462, AAH52462
RefSeq Size 5588 bp
RefSeq ORF 4505 bp
Locus ID 19280
Gene Summary Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans (PubMed:19833921, PubMed:21454754, PubMed:22406547). Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth (PubMed:21454754). Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection (PubMed:15797710, PubMed:19833921, PubMed:19780196, PubMed:21454754, PubMed:22519304, PubMed:22406547). Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2 (PubMed:21454754). Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb (PubMed:10080191). Functions as tyrosine phosphatase (PubMed:7529177). Mediates dephosphorylation of NTRK1, NTRK2 and NTRK3 (By similarity). Plays a role in down-regulation of signaling cascades that lead to the activation of Akt and MAP kinases (PubMed:15797710). Down-regulates TLR9-mediated activation of NF-kappa-B, as well as production of TNF, interferon alpha and interferon beta (PubMed:26231120).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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