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Adcy6 (NM_007405) Mouse Untagged Clone
CAT＃: MC223787
Adcy6 (untagged) - Mouse adenylate cyclase 6 (Adcy6), (10ug)
CN¥ 15,010.00
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Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AC6; mKIAA0422 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223787 representing NM_007405
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCATGGTTTAGTGGCCTCCTGGTTCCCAAAGTGGATGAACGGAAAACAGCTTGGGGGGAACGCAATG GGCAGAAGCGCCCACGCCACGCGAATCGAGCCAGTGGCTTCTGCGCACCTCGCTACATGAGCTGCCTCAA GAATGCGGAGCCACCCAGCCCCACTCCTGCAGCTCACACTCGGTGCCCCTGGCAGGATGAAGCCTTCATC AGGAGGGCGGGCCCGGGCAGGGGTGTGGAGCTGGGGCTGCGGTCAGTGGCCTTGGGGTTTGACGACACTG AGGTGACCACACCGATGGGCACAGCTGAAGTGGCACCGGATACATCGCCTCGGAGCGGTCCGTCCTGCTG GCACCGGCTTGTGCAGGTGTTCCAGTCTAAGCAGTTCCGCTCTGCCAAGCTGGAGCGGCTGTACCAGCGG TACTTCTTCCAGATGAACCAGAGCAGCCTCACGCTGCTCATGGCGGTGCTGGTGCTGCTCATGGCTGTAC TGTTGACTTTCCACGCTGCGCCTGCCCAGCCTCAGCCTGCTTACGTGGCCCTGCTGACCTGTGCCTCTGT CCTTTTTGTGGTACTCATGGTGGTGTGTAACCGACACAGCTTCCGCCAGGACTCCATGTGGGTGGTGAGC TATGTGGTCCTGGGCATCCTAGCAGCCGTGCAAGTCGGGGGTGCCCTGGCAGCCAATCCACACAGCCCCT CGGCGGGCCTTTGGTGCCCCGTGTTCTTCGTCTACATCACCTACACTCTTCTTCCCATTCGCATGCGAGC CGCAGTACTCAGCGGCCTGGGCCTCTCTACTCTGCATTTGATTTTGGCCTGGCAGCTCAACAGCAGCGAC CCCTTCCTTTGGAAGCAGCTCGGTGCTAACGTGGTGCTCTTCCTCTGCACCAATGCCATCGGTGTCTGCA CACACTACCCTGCTGAAGTGTCTCAGCGCCAAGCCTTTCAGGAGACCCGAGGTTACATCCAGGCGCGGCT GCACCTGCAGCATGAGAACCGTCAGCAGGAACGGCTGCTGCTATCGGTGTTGCCCCAGCACGTTGCCATG GAGATGAAAGAAGACATCAACACAAAAAAAGAGGACATGATGTTCCATAAGATCTACATCCAGAAGCATG ATAATGTCAGCATCCTGTTTGCGGACATTGAGGGCTTCACCAGCCTGGCCTCCCAGTGCACTGCACAGGA ACTGGTCATGACCTTGAATGAGCTCTTTGCCCGGTTTGACAAGCTGGCTGCGGTGAGGGAGAATCACTGT CTGAGGATCAAGATCTTAGGAGACTGTTACTACTGCGTGTCAGGGCTGCCCGAGGCCCGGGCAGATCACG CCCACTGCTGTGTGGAGATGGGGGTAGACATGATCGAAGCCATCTCGCTGGTGCGTGAGGTAACAGGTGT GAACGTGAACATGCGTGTGGGCATCCACAGCGGACGTGTGCATTGCGGCGTCCTTGGCCTACGGAAATGG CAGTTTGATGTCTGGTCAAACGATGTGACCCTGGCTAACCACATGGAGGCCGGGGGCCGGGCCGGCCGCA TCCACATCACTCGGGCTACACTGCAGTACTTGAACGGGGACTATGAGGTGGAGCCAGGCCGTGGTGGTGA ACGCAATGCGTACCTCAAGGAGCAGTGCATTGAGACCTTCCTCATACTTGGCGCCAGCCAAAAACGGAAA GAGGAGAAAGCCATGCTGGCCAAGCTTCAGCGGACACGGGCCAACTCCATGGAAGGACTGATGCCCCGCT GGGTTCCTGACCGTGCCTTCTCCCGGACCAAGGACTCTAAGGCATTCCGCCAGATGGGCATTGATGATTC TAGCAAAGACAACCGGGGTGCCCAAGATGCTCTGAACCCTGAAGATGAGGTGGATGAGTTCCTGGGCCGA GCCATCGATGCCCGAAGCATCGACCAACTGCGTAAGGACCATGTGCGCCGGTTCCTGCTCACCTTCCAGA GAGAGGATCTTGAGAAGAAGTATTCACGGAAAGTAGATCCTCGCTTCGGAGCCTACGTCGCCTGTGCCCT CCTGGTTTTTTGCTTCATCTGTTTTATCCAGCTCCTTGTGTTCCCATACTCCACCCTGATACTCGGGATT TATGCCGCTATCTTCCTGCTGTTGCTGGTCACTGTGCTGATCTGTGCCGTGTGCTCCTGCGGTTCTTTCT TCCCCAAGGCCCTGCAACGCCTGTCCCGCAATATTGTCCGCTCACGGGTGCACAGCACCGCGGTTGGAAT CTTCTCGGTTCTGCTTGTGTTCATCTCTGCCATCGCCAACATGTTTACCTGTAATCACACCCCAATAAGG ACCTGCGCGGCCCGGATGCTGAACTTAACACCAGCGGATGTCACCGCCTGCCACCTACAACAGCTCAATT ACTCTCTGGGACTGGATGCTCCCCTGTGTGAGGGCACCGCACCCACCTGCAGCTTCCCTGAGTACTTCGT CGGGAACGTGCTGCTGAGTCTTCTAGCCAGCTCTGTCTTCCTACACATCAGCAGCATCGGCAAGCTGGCC ATGACCTTCATCTTGGGGTTCACCTACTTGGTGCTGCTTTTGCTGGGTCCCCCGGCCGCCATCTTTGACA ACTATGATCTACTGCTTGGCGTCCATGGCTTGGCTTCCTCCAATGAGACCTTTGATGGGCTGGACTGCCC AGCTGTGGGGAGGGTAGCGCTCAAATATATGACCCCCGTGATTCTGCTGGTGTTTGCCCTGGCACTGTAT CTGCATGCACAACAGGTGGAATCGACTGCCCGCCTGGACTTCCTGTGGAAGTTACAGGCAACAGGGGAGA AGGAGGAGATGGAGGAGCTACAGGCATACAACCGGAGGTTGCTGCATAACATTCTTCCCAAGGACGTGGC CGCCCACTTCCTGGCCCGGGAACGCCGCAACGATGAGCTGTACTACCAGTCGTGTGAATGTGTGGCTGTC ATGTTTGCCTCCATCGCCAATTTCTCGGAGTTCTACGTGGAGCTCGAGGCAAACAACGAGGGCGTGGAGT GCCTGCGGCTGCTCAATGAGATCATCGCAGACTTTGACGAGATCATCAGTGAGGAGAGATTCCGGCAGTT GGAGAAGATCAAGACCATCGGTAGCACCTACATGGCCGCCTCTGGGCTAAATGCCAGCACCTATGACCAG GTCGGCCGCTCACACATCACGGCGCTGGCTGACTATGCCATGCGGCTCATGGAGCAGATGAAACACATCA ATGAACACTCTTTCAACAATTTCCAGATGAAGATCGGGTTGAACATGGGTCCGGTTGTAGCAGGCGTCAT TGGGGCCCGAAAGCCACAGTATGACATCTGGGGAAATACCGTGAATGTTTCCAGTCGTATGGACAGCACT GGAGTTCCTGACCGAATACAGGTGACTACGGACCTATACCAGGTTCTAGCTGCCAAGGGCTACCAGCTGG AGTGTCGAGGGGTGGTCAAGGTGAAGGGAAAGGGGGAGATGACCACCTACTTCCTCAACGGGGGCCCCAG CAGTTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_007405 |
| Insert Size | 3507 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007405.2, NP_031431.2 |
| RefSeq Size | 6038 bp |
| RefSeq ORF | 3507 bp |
| Locus ID | 11512 |
| UniProt ID | Q01341 |
| Gene Summary | Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:18071070, PubMed:24363043). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells (PubMed:18071070). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption (PubMed:20466003, PubMed:20864687). Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion (PubMed:24854272). Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (PubMed:23753526). Signaling mediates cAMP-dependent activation of protein kinase PKA and promotes increased phosphorylation of various proteins, including AKT (PubMed:18071070, PubMed:23753526). Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility (PubMed:18071070). May contribute to normal heart function (PubMed:18071070, PubMed:20359598). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (By similarity). Contributes to bone cell responses to mechanical stimuli (PubMed:20371630, PubMed:24277577).[UniProtKB/Swiss-Prot Function] |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226872 | Adcy6 (tGFP-tagged) - Mouse adenylate cyclase 6 (Adcy6), (10ug) |
CN¥ 10,550.00 |
|
| MR226872 | Adcy6 (Myc-DDK-tagged) - Mouse adenylate cyclase 6 (Adcy6) |
CN¥ 8,136.00 |
|
| MR226872L3 | Lenti ORF clone of Adcy6 (Myc-DDK-tagged) - Mouse adenylate cyclase 6 (Adcy6) |
CN¥ 11,500.00 |
|
| MR226872L4 | Lenti ORF clone of Adcy6 (mGFP-tagged) - Mouse adenylate cyclase 6 (Adcy6) |
CN¥ 11,500.00 |
