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Adcy6 (NM_007405) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR226872L4V
- LentiORF®
-
Lenti ORF particles, Adcy6 (GFP-tagged) - Mouse adenylate cyclase 6 (Adcy6), 200ul, >10^7 TU/mL
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CNY 19,000.00
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Specifications
| Product Data | |
| Product Name | Adcy6 (NM_007405) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AC6; mKIAA0422 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_007405 |
| ORF Size | 3504 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR226872).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_007405.2 |
| RefSeq Size | 6038 bp |
| RefSeq ORF | 3507 bp |
| Locus ID | 11512 |
| Gene Summary | Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:18071070, PubMed:24363043). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells (PubMed:18071070). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption (PubMed:20466003, PubMed:20864687). Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion (PubMed:24854272). Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (PubMed:23753526). Signaling mediates cAMP-dependent activation of protein kinase PKA and promotes increased phosphorylation of various proteins, including AKT (PubMed:18071070, PubMed:23753526). Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility (PubMed:18071070). May contribute to normal heart function (PubMed:18071070, PubMed:20359598). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (By similarity). Contributes to bone cell responses to mechanical stimuli (PubMed:20371630, PubMed:24277577).[UniProtKB/Swiss-Prot Function] |
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