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Mark3 (NM_022801) Mouse Untagged Clone
CAT＃: MC221156
Mark3 (untagged) - Mouse MAP/microtubule affinity-regulating kinase 3 (Mark3), transcript variant 2, (10ug)
CNY 9,500.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1600015G02Rik; A430080F22Rik; C-TAK1; Emk2; ETK-1; ETK1; MPK10 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221156 representing NM_022801
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCCACTAGGACCCCTTTGCCAACGGTGAATGAACGAGACACTGAAAACCACATTTCACATGGAGACG GGAGGCAAGAAGTCACCTCCCGCACCGGGCGCTCTGGAGCTCGGTGTAGAAACTCAATAGCTTCCTGTGC AGATGAACAGCCTCACATCGGAAACTACAGACTGTTGAAAACAATCGGCAAGGGGAACTTTGCAAAAGTG AAATTGGCGAGACACATCCTCACAGGCCGAGAGGTTGCAATAAAAATAATTGACAAAACTCAGTTGAATC CAACAAGTCTACAAAAGCTCTTCAGAGAAGTAAGAATAATGAAGATTTTAAATCACCCAAACATAGTGAA GTTGTTCGAAGTCATTGAAACGGAAAAAACTCTCTACTTAATCATGGAATATGCAAGTGGAGGTGAAGTA TTTGACTATTTGGTTGCACATGGAAGAATGAAGGAAAAAGAAGCAAGAGCTAAATTTAGACAGATTGTTT CCGCAGTACAGTATTGCCACCAAAAACGGATTGTTCACAGAGACCTCAAGGCTGAAAATCTGTTATTAGA TGCGGATATGAACATTAAAATAGCAGATTTTGGTTTTAGCAATGAATTTACTGTTGGCAGTAAACTAGAC ACGTTTTGTGGTAGTCCTCCATATGCAGCCCCTGAGCTCTTCCAGGGCAAGAAGTATGACGGGCCAGAAG TCGACGTGTGGAGCCTCGGTGTCATTCTCTACACCCTAGTCAGTGGGTCGCTTCCCTTTGATGGTCAAAA CCTGAAGGAACTGAGAGAGAGAGTACTCCGCGGGAAGTACAGAATCCCTTTCTACATGTCCACAGACTGC GAGAACCTTCTCAAGCGCTTCCTGGTGCTGAACCCAGTTAAACGGGGCACTCTCGAGCAAATCATGAAGG ACAGGTGGATCAATGCAGGCCATGAGGAGGATGAGCTTAAGCCATTTGTTGAACCAGAACTAGACATCTC AGACCAGAAGAGAATAGATATTATGGTGGGAATGGGATATTCCCAAGAAGAAATTCAAGAATCTCTTAGC AAAATGAAATACGATGAAATCACAGCTACTTACTTGCTACTGGGGAGGAAATCTGCAGAGCTGGACGCTA GTGACTCCAGTTCTAGCAGCAACCTTTCACTTGCTAAGGTGCGGCCAAACAGTGACCTCAGCAATAGCAC TGGCCAGTCTCCTCATCACAAAGGGCAGAGAAGTGTTTCCTCAAGTCAGAAGCAGAGACGGTACAGTGAC CACGCTGGACCAGCTATTCCTTCAGTTGTGGCATATCCAAAGAGGAGTCAGACCAGCACTGCAGATAGTG ACCTCAAAGAAGATGGAATTCCCTCCCGAAAATCAAGCAGCAGTGCTGTAGGAGGGAAGGGGATTGCTCC TGCCAGTCCCATGCTTGGGAATGCAGGCAATCCCAATAAAGCCGATATCCCTGAGCGCAAGAAAAGCCCT GCTGTGCCCAGTAGTAACACAGCATCTGGTGGGATGACACGGCGGAACACTTACGTTTGCAGCGAGAGAT GTGCAGCAGACAGACATTCTGTGATTCAGAACGGCAAAGAAAACAGCGCTATTCCAGATGAGAGAACTCC AGTTGCTTCAACCCACAGTATTAGCAGTGCGACCACCCCAGATCGCATCCGCTTTCCAAGGGGCACAGCC AGCCGTAGCACTTTCCATGGCCAACCTCGGGAGCGGCGAACCGCAACATATAATGGCCCACCTGCCTCAC CCAGCTTGTCCCATGAAGCCACACCGCTGTCTCAGACTCGAAGCCGAGGTTCCACTAATCTTTTTAGTAA ATTAACTTCCAAACTCACAAGAAGTCGCAATGTGTCTTCAGAGCAGAAGGATGAGAACAGAGAGGCCAAG CCCCGCTCCCTGCGCTTCACCTGGAGCATGAAGACCACGAGCTCCATGGACCCCAGTGACATGATGCGGG AGATCCGCAAGGTGCTGGACGCCAATAACTGCGACTACGAGCAGAGGGAGCGCTTCCTGCTCTTCTGTGT CCATGGCGACGGGCACGCAGAGAACCTGGTACAGTGGGAAATGGAAGTCTGTAAGCTGCCAAGACTGTCT CTGAATGGAGTCCGGTTTAAGCGGATATCAGGGACATCCATAGCTTTCAAAAATATTGCTTCCAAAATTG CCAATGAGCTAAAGCTGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_022801 |
| Insert Size | 2190 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022801.4, NP_073712.2 |
| RefSeq Size | 3343 bp |
| RefSeq ORF | 2190 bp |
| Locus ID | 17169 |
| UniProt ID | Q03141 |
| Gene Summary | Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAPT/TAU, MAP2 and MAP4. Phosphorylates CDC25C. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The encoded isoform (2) is shorter than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227365 | Mark3 (tGFP-tagged) - Mouse MAP/microtubule affinity-regulating kinase 3 (Mark3) transcript variant 2, (10ug) |
CNY 8,080.00 |
|
| MR227365 | Mark3 (Myc-DDK-tagged) - Mouse MAP/microtubule affinity-regulating kinase 3 (Mark3), transcript variant 2 |
CNY 7,320.00 |
|
| MR227365L3 | Lenti ORF clone of Mark3 (Myc-DDK-tagged) - Mouse MAP/microtubule affinity-regulating kinase 3 (Mark3), transcript variant 2 |
CNY 9,220.00 |
|
| MR227365L4 | Lenti ORF clone of Mark3 (mGFP-tagged) - Mouse MAP/microtubule affinity-regulating kinase 3 (Mark3), transcript variant 2 |
CNY 9,220.00 |
