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Mark3 (NM_022801) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR227365L3V
- LentiORF®
-
Lenti ORF particles, Mark3 (Myc-DDK-tagged) - Mouse MAP/microtubule affinity-regulating kinase 3 (Mark3), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 12,160.00
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规格
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Specifications
| Product Data | |
| Product Name | Mark3 (NM_022801) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1600015G02Rik; A430080F22Rik; C-TAK1; Emk2; ETK-1; ETK1; MPK10 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_022801 |
| ORF Size | 2187 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR227365).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_022801.4, NP_073712.2 |
| RefSeq Size | 3343 bp |
| RefSeq ORF | 2190 bp |
| Locus ID | 17169 |
| Gene Summary | Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAPT/TAU, MAP2 and MAP4. Phosphorylates CDC25C. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1.[UniProtKB/Swiss-Prot Function] |
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