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Alox12 (NM_007440) Mouse Untagged Clone
CAT＃: MC220231
Alox12 (untagged) - Mouse arachidonate 12-lipoxygenase (Alox12), (10ug)
CNY 8,550.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 9930022G08Rik; Alox12p; P-12LO |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC220231 representing NM_007440
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGCCGCTACCGCGTCCGTGTGGTCACTGGGGCCTGGCTCTTCTCCGGATCCCTCAACCTAGTGCGTT TGTGGCTGGTTGGGGAGCACCGGGAGGCGAAACTGGAGCTGCAACTGCGGCCAGCGCGGGGCAAGGAGGA GGAGTTTGACTTCGACGTTCCCGAGGACTTGGGGCCACTGCAGTTTGTGAAACTGCACAAACAGCACACA GTTGTGGATGACGCCTGGTTCTGCAACCTCATCACAGTTCAGGGGCCGGGGACAAGTGCAGAGGCCGTGT TTCCCTGCTACCGCTGGGTGCAGGGAGAGGGAATCCTGAGCCTCCCGGAGGGGACAGCCCGCCTGGCAGG AGACAATGCCTTAGATGTCTTCCAGAAGTATCGAGAAAAGGAACTGAAGGAAAGACAACAGACCTACTGC TGGGCCACCTGGAAAGAAGGCTTACCTCAGACAATAGCAGCGGACTGTAAGGATGACCTTCCTCCAAATA TGAGATTCCATGAGGAGAAGAGACTGGACTTTGAATGGACGTTGAAGGCGGGGGTTCTGGAAATGGGCCT CAAACGTGTTTATACCCTCCTGAGAAGCTGGAACCATCTGGAAGACTTTGATCAGATCTTCTGGGGCCAG AAGAGTGCCTTGGCCGAGAAGGTTCACCAGTGTTGGCAGGAAGATGAACTCTTTGGCTACCAGTTCCTCA ATGGCGCCAACCCCATGCTTTTGAGACGCTCCACCTCTCTGCCCTCCAGACTGGTACTGCCCTCTGGGAT GGAGGAGCTTCAAGCTCAGTTGGAGAAAGAACTCAAGAATGGATCCCTGTTTGAAGCTGACTTTATCCTG CTGGATGGAATTCCAGCTAATGTGATCCGAGGAGAACCACAGTACCTGGCTGCCCCTCTTGTCATGCTGA GGATGGACCCCGGTGGGAAGCTGCTACCCATGGCTATCCAGATTCAGCCCCCTAACCCCAGCTCCCCAGC TCCAACACTGTTCCTGCCCTCGGATCCTCCACTTGCCTGGCTCTTGGCTAAGATCTGGGTCCGAAATTCA GATTTCCAACTGCAGGAGCTCCAATTCCATTTGCTGAACACCCATCTGGTGGCTGAGGTCATCGCTGTTG CCACCATGAGATGCCTCCCAGGACTGCACCCTATCTTCAAGCTCCTCGTTCCACACATCCGTTACACTAT GGAAATTAACACGCGAAGCCGGACCCAGCTCATCTCAGATGGAGGAATATTTGATCAGGTAGTGAGCACA GGTGGAGGCGGCCATGTTCAGTTGCTTACTCGGGCAGTGGCTCAGCTGACTTACCACTCCCTCTGTCCTC CTGATGATCTGGCTAACCGAGGCCTGCTGAGAATCCCAAGTGCTCTCTATGCTCGGGATGCTTTACAGCT CTGGGAAGTCACTGCCAGGTATGTGAAGGGGATGGTCCATCTCTTCTACCAGAGTGATGATATTGTGAGG GGAGACCCAGAGCTGCAGGCCTGGTGTCGGGAGATCACTGAAGTGGGGCTGTGCCATGCCCAGGACAGAG GATTCCCTGTCTCCTTCCAGTCCCGGGCTCAGCTCTGCCATTTCCTCACCATGTGTGTTTTCACATGCAC TGCCCAGCATGCTGCCATCAACCAGGGCCAGCTGGACTGGTATGGTTGGGTACCTAATGCTCCATGCACA ATGAGGATGCCTCCGCCCACCAGCAAGGACGACGTGACGATGGAGACCGTGATGGGGTCGCTACCTGATG TGCAGAAGGCCTGTCTTCAGATGACTATCACATGGCACCTGGGTCGCCTGCAGCCAGACATGGTACCTCT AGGACACCACACAGAAAAATATTTCTCAGACCCAAGGACCAAAGCTGTGCTCAGCCAATTTCAAGCAGAT TTGGACAATTTGGAGAAAGAGATTACAGCCCGGAATGAGCAACTTGACCTGCCTTATGAATACCTCAAGC CCAGCCGCATAGAGAACAGTATCACCATCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_007440 |
| Insert Size | 1992 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007440.4, NP_031466.2 |
| RefSeq Size | 2991 bp |
| RefSeq ORF | 1992 bp |
| Locus ID | 11684 |
| UniProt ID | P39655 |
| Gene Summary | Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longer isoform (1). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227302 | Alox12 (tGFP-tagged) - Mouse arachidonate 12-lipoxygenase (Alox12), (10ug) |
CNY 6,370.00 |
|
| MR227302 | Alox12 (Myc-DDK-tagged) - Mouse arachidonate 12-lipoxygenase (Alox12) |
CNY 4,936.00 |
|
| MR227302L3 | Lenti ORF clone of Alox12 (Myc-DDK-tagged) - Mouse arachidonate 12-lipoxygenase (Alox12) |
CNY 7,700.00 |
|
| MR227302L4 | Lenti ORF clone of Alox12 (mGFP-tagged) - Mouse arachidonate 12-lipoxygenase (Alox12) |
CNY 7,700.00 |
