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Cep290 (BC004690) Mouse Untagged Clone
CAT＃: MC218579
Cep290 (untagged) - Mouse centrosomal protein 290 (cDNA clone MGC:7859 IMAGE:3501291), (10ug)
CNY 6,940.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | MGC7859 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for BC004690 edited
CCCACGCGTCCGAGCAAAGAGAAATTGTTAAGAAGCATGAGGAAGACCTTCATGTTCTTCATCACAAATT AGAACAACAGGCCGATAATTCACTCAATAAATTCAGACAGACAGCTCAGGATTTACTTAAGCAGTCTCCT GCTCCAGTTCCCACCAACAAACATTTCATTCGTCTGGCCGAGATGGAGCAGACAGTAGCAGAACAAGATG ACTCTCTGTCCTCACTTTTGACCAAACTAAAGAAAGTATCAAAAGATTTGGAAAAACAAAAAGAAATCAC TGAGTTAAAAGTCAGAGAGTTTGAAAATACCAAACTACGGCTCCAAGAAACTCATGCCAGTGAGGTAAAG AAAGTGAAAGCAGAGGTAGAGGACTTAAGGCATGCTCTAGCCCAAGCACACAAGGACTCCCAGAGTTTAA AGTCTGAACTCCAGGCTCAGAAAGAAGCAAACTCCAGAGCTCCAACAACCACAATGAGGAATCTTGTAGA AAGGCTAAAGAGCCAACTAGCCTTGAAAGAGAAGCAACAAAAGGCACTTAGTCGAGCCCTGTTGGAACTT CGGTCGGAAATGACAGCAGCAGCTGAGGAACGTATAATCGCTGTAACTTCTCAAAAAGAGGCAAATCTCA ATGTTCAACAAGTTGTTGAGCGCCATACTAGAGAGCTAAAGTCACAAATTGAAGATTTAAATGAAAATCT TTTAAAATTGAAAGAAGCTCTTAAAACAAGTAAGAACAAAGAAAATTCACTAGCTGATGATTTAAATGAA TTAAATAATGAACTGCAAAAAAAGCAAAAAGCTTATAATAAAATCCTTAGAGAGAAAGATGGAATTGATC AAGAAAATGATGAACTGAGAAGACAGATTAAAAGACTGTCCAGTGGACTGCAGAGCAAAACTTTGATAGA TAACAAGCAAAGTTTAATCGATGAACTTCAAAAGAAAGTTAAAAAACTTGAAAGCCAACTGGAAAGAAAG GTGGATGACGTAGACATAAAGCCGGTGAAGGAAAAGAGTAGTAAAGAAGAATTAATTAGGTGGGAAGAAG GTAAGAAATGGCAAACCAAAGTAGAGGGACTACGAAACAGACTAAAGGAGAAGGAAGGAGAAGCCCACGG CCTGGCAAAGCAGCTGAATACCTTAAAGGAACTTTTTGCCAAAGCTGATAAAGAGAAACTTACTTTGCAG AAGAAACTGAAAACAACAGGAATGACTGTTGACCAGGTTTTAGGAGTGCGAGCTTTGGAATCTGAAAAAG AGTTGGAAGAGCTAAAAAAGAAAAATCTGGACCTAGAAAATGACATATTATACATGAGGACCCAGCAGGC TCTTCCACGAGATTCTGTTGTGGAAGACTTACATTTACAAAATAAATACCTTCAAGAAAAACTTCATACT TTAGAAAAAAAACTTTCAAAGGAGAAAATTGTTGCCGAAAATGAACGGCTTCGGAAAGAACTTAAGAAAG AAATAGAAGCCTCTGAGAAACTGCGGATAGCTAAGAACAACTTAGAGCTGGTGAACGACAAGATGGCAGC TCAACTCGAAGAAACTGGGAAGAGACTACAGTTTGCAGAAAGTAGAGCCCCACAGCTGGAAGGTGCTGAC AGCAAGAGCTGGAAGTCAATTGTGGTCTCAAGAGTGTATGAGACCAAGATGAAAGAGCTTGAAAGTGACA TTGCCAAAAAGAATCAAAGTATCACTGACCTTAAACAGCTTGTAAGAGAAGCAACAGAGAGAGAACAGAA AGCTAAGAAATACACTGAAGACCTTGAACAACAGATTGAGATCCTCAAAAATGTTCCTGAAGGTGCCGAG ACAGAGCAAGAGCTTATACGGGAACTCCAGCTTCTTAGATTAGCCAATAATCAGCTGGATAAAGAAAGGG CAGAATTAATCCATCAGATAGAAATTAACAAGGACCAAACCAGAGCTGACAGTAGCATACCTGATTCTGA TCAACTAAAGGAAAAGATAAATGACCTGGAGACACAACTCAGAAAGTTGGAGCTAGAAAAGCAACATTCG AAGGAGGAAGTTAAAAAGCTGAAAAAAGAACTGGAAAATTTTGATCCTTCATTTTTTTGAAGAAATTGAA GACCTGAAGTATAATTATAAGGAAGAAGTGAAAAAGAATATCCTATTAGAAGAGAAGCTAAAAAAACTGT CGGAACAGTTTGGATTTGAACTGCCTAGTCCTCTTGCTGCTTCTGAACACTCGGAAGATGGAGAAAGTCC TCATAGTTTCCCTATTTATTAGTGCCCTCGTGTAACTGCAGGTTTAAAACTATTTTATGAGTGAAAAAAG TTTCAGCTGGAAATCAAGCAGTCTCTGTGTTATAGAATTTACAGCTCAAAATATTGTATTTTTTTTGTTT AAAAAAATCATATTTAGTTTTAACTTGTTAGAAAAGTATATTTTTGAAGACTTCATTAATTTATGACTAT ACAGTGCACAATGAGCTATGATAAATATTACTATTTTCATAATAACTTAAATTTTCAAAAAGCATAAAGG TAAGCTTATATCAATTTACTATTTAAAATTGATTATTTTATATTTATTTTTGTGTTAAGATAGTCAAATC CTAACGATGATTTCTATAAATACCTAGAAACATGTTTAGAAGTTGACAGGTTTTGCCAAACAGCTAGCAA AATTAAATGCAAACTATTCAGTCTTAGAAAATCACAATAATCTCAACAATTAGTTCCATTTTATACATCA AGTATTATGTCTTTGAGTCTCTCAAATTTCTGTTTATCTATTTTTGAAAACTGATTAAACAAAGACTGGT |
| Restriction Sites | SgfI-MluI |
| ACCN | BC004690 |
| Insert Size | 1176 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC004690.1 |
| RefSeq Size | 2831 bp |
| RefSeq ORF | 1907 bp |
| Locus ID | 216274 |
| Gene Summary | Involved in early and late steps in cilia formation (PubMed:21565611). Its association with CCP110 is required for inhibition of primary cilia formation by CCP110 (By similarity). May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1 (By similarity). Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes (PubMed:16632484). Required for efficient recruitment of RAB8A to primary cilium (By similarity). In the ciliary transition zone is part of the tectonic-like complex (also named B9 complex) which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (PubMed:21725307). Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2, BBS5 and BBS8/TTC8 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating IQCB1/NPHP5 (By similarity). Activates ATF4-mediated transcription (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209644 | Cep290 (tGFP-tagged) - Mouse centrosomal protein 290 (cDNA clone MGC:7859 IMAGE:3501291) |
CNY 9,168.00 |
|
| MR209644 | Cep290 (Myc-DDK-tagged) - Mouse centrosomal protein 290 (cDNA clone MGC:7859 IMAGE:3501291) |
CNY 6,370.00 |
|
| MR209644L3 | Lenti ORF clone of Cep290 (Myc-DDK-tagged) - Mouse centrosomal protein 290 (cDNA clone MGC:7859 IMAGE:3501291) |
CNY 8,270.00 |
|
| MR209644L4 | Lenti ORF clone of Cep290 (mGFP-tagged) - Mouse centrosomal protein 290 (cDNA clone MGC:7859 IMAGE:3501291) |
CNY 8,270.00 |
