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Usp30 (NM_001033202) Mouse Untagged Clone
CAT＃: MC217339
Usp30 (untagged) - Mouse ubiquitin specific peptidase 30 (Usp30), (10ug)
CNY 6,650.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 6330590F17Rik; AI851327; D5Ertd483e |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC217339 representing NM_001033202
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTAAGTTCCCGGGCGCAGGCGGCGAGGACGGCGGCCGACAAGGCCCTGCAGCGCTTCCTGCGCACCG GGGCGGCCGTCAGATACAAAGTCATGAAGAACTGGGGAGTGATCGGTGGGATTGCCGCTGCCCTGGCAGC AGGGATCTATGTTATTTGGGGTCCCATTACAGAGAGGAAGAAGCGGAGAAAAGGGCTTGTGCCTGGCCTT GTCAATCTGGGGAATACCTGCTTCATGAACTCGCTGCTGCAGGGCCTGTCTGCCTGCCCTGCGTTTGTCA AGTGGCTGGAAGAGTTTACCACCCAGTACTCCAGGGACCAGCAGGGGCCACACACTCACCAGTGCCTGTC CTTAACACTGCTGAACCTCCTGAAAGCTCTGTCCTGCCAAGAAGTCACCGAGGACGAGGTCTTGGACGCC AGCTGTCTGCTGGACGTCCTGAGAATGTACAGATGGCAGATCTCGTCCTTTGAGGAGCAGGATGCTCACG AGCTGTTTCATGTCATCACCTCATCACTGGAGGACGAGAGAGACCGCCAGCCTCGAGTCACCCACTTGTT TGATGTGCATTCCCTGGAGCAGCAGTCAGAAATGGCTCCCAGACAAGTCACTTGCCACACGAGAGGGTCC CCTCACCCCACGACCAATCACTGGAAGTCTCAGCACCCTTTCCATGGAAGACTCACCAGTAACATGGTGT GCAAACACTGTGAACACCAGAGTCCTGTTCGGTTTGACACCTTTGACAGCCTTTCTCTCAGTATTCCAGC TGCCACTTGGGGGCACCCACTGACACTGGACCACTGCCTTCACCACTTCATCTCATCAGAGTCCGTGCGA GACGTTGTGTGTGACAACTGTACAAAGATTGAAGCGAGGGGGACACTGACCGGGGAGAAGGTGGAGCATC AGAGGAGCACCTTTGTTAAACAGTTAAAACTCGGAAAGCTGCCACAGTGCCTCTGCATCCACCTGCAGCG GCTCAGCTGGTCCAGCCACGGCACGCCCTTGAAGCGGCACGAGCACGTGCAGTTTAACGAGTTCCTGATG ATGGACTTCTACAAGTACCGCCTCCTGGGACACAAGCCCAGCCAGCATGGCCCCAAAGCCACCGAGAACC CAGGGTCTGCCCCAGAAGTACAGGACGCACAGGCGGCCCCAAAGCCAGGTCTGAGTCAGCCAGGGGCCCC CAAGACACAGATTTTTCTGAATGGCGCCTGCTCCCCGTCTCTGTTGCCAGCCCTGCCTTCCCCGGTGGCC TTCCCTCTGCCAGTGGTTCCTGACTACAGCTCCTCCACATACCTCTTCCGCTTGATGGCAGTTGTCGTTC ACCATGGAGACATGCACTCTGGACACTTTGTCACCTACAGACGGTCACCACCTTCTGCCAAGAACCCTCT CTCAACCAGCAACCAATGGCTGTGGATTTCTGACGACACCGTCCGCAAGGCCAGCCTGCAGGAGGTCCTG TCCTCTAGTGCCTACCTGCTGTTCTATGAGCGAGTTCTGTCCAGGGTGCAGCAGCAGGGGCGAGAGTATA GGTCTGAGGAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001033202 |
| Insert Size | 1554 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001033202.3, NP_001028374.1 |
| RefSeq Size | 2790 bp |
| RefSeq ORF | 1554 bp |
| Locus ID | 100756 |
| UniProt ID | Q3UN04 |
| Gene Summary | Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy. Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate in mitophagic signaling. Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65' (By similarity). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 (PubMed:24513856).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226441 | Usp30 (tGFP-tagged) - Mouse ubiquitin specific peptidase 30 (Usp30), (10ug) |
CNY 5,448.00 |
|
| MR226441 | Usp30 (Myc-DDK-tagged) - Mouse ubiquitin specific peptidase 30 (Usp30) |
CNY 3,848.00 |
|
| MR226441L3 | Lenti ORF clone of Usp30 (Myc-DDK-tagged) - Mouse ubiquitin specific peptidase 30 (Usp30) |
CNY 6,370.00 |
|
| MR226441L4 | Lenti ORF clone of Usp30 (mGFP-tagged) - Mouse ubiquitin specific peptidase 30 (Usp30) |
CNY 6,370.00 |
