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Dmrt1 (NM_015826) Mouse Untagged Clone
CAT＃: MC209870
Dmrt1 (untagged) - Mouse doublesex and mab-3 related transcription factor 1 (Dmrt1), (10ug)
CNY 3,656.00
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC209870 representing NM_015826
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCGAACGACGACACATTCGGCAAGCCCTCTACCCCGACGGAGGTTCCTCACGCTCCCGGGGCCCCGC CGCAGGGCAAAGCCGGAGGTTACAGCAAAGCTGCCGGGGCGATGGCTGGAGCGGCTGGAGGCTCGGGCGC GGGGGGCAGCGGAGGTGCCTCGGGCTCCGGGCCGTCGGGCCTGGGTTCTGGAAGCAAGAAGTCCCCGAGG CTGCCCAAATGCGCTCGCTGCAGGAACCACGGCTACGCGTCGCCGCTCAAGGGCCACAAGCGCTTCTGCA TGTGGCGGGATTGCCAGTGCAAGAAGTGCAGCCTGATTGCGGAGCGACAGCGGGTGATGGCCGCGCAGGT GGCCCTGAGAAGACAGCAGGCCCAGGAAGAAGAACTGGGTATCAGCCACCCAATTCCGCTGCCCAGCGCA GCCGAGCTCCTGGTCAAAAGAGAGAATAATGCCAGCAACCCGTGCCTGATGGCCGAGAACAGCAGCTCTG CCCAGCCCCCACCGGCCAGCACCCCAACCCCCGCTGCCTCAGAGGGACGCATGGTCATCCAGGATATTCC TGCTGTCACCAGCAGAGGGCATATGGAGAACACATCTGACCTGGTATCAGACCCCGCCTACTACAGCAGC TTTTACCAGCCTTCTCTGTTTCCTTACTACAACAATCTGTACAACTACCCCCAGTATTCCATGGCCTTGT CTGCTGAGTCCTCCTCAGGGGAGGTGGGGAATTCCCTCGGGGGATCCCCCGTGAAGAACAGCCTGCGGAG TCTCCCAGCACCTTACGTGCCTGCTCAGACTGGAAACCAGTGGCAGATGAAGACCTCAGAGAGCCGCCAC CCAGTGAGCTCCCAGTACCGGATGCACTCATACTACGGGCCTCCCTCCTACCTGGGCCAGAGCATGTCCC AGATCTTTACCTTCGAGGAAGGCCCCTCCTACTCAGAAGCCAAAGCCAGTGTGTTCTCGCCCCCCAGCAG TCAAGATTCTGGCTTGGTCTCCCTCTCCAGCAGCTCTCCGATGAGCAACGAGAGCTCGAAGGGAGTTCTG GAATGTGAGTCTGCGTCCTCGGAACCTAGCAGCTACGCCGTCAACCAGGTCCTGGAAGAGGATGAGGACG AGTGAAGCGGACCG AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-RsrII |
| ACCN | NM_015826 |
| Insert Size | 1134 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015826.5, NP_056641.2 |
| RefSeq Size | 2251 bp |
| RefSeq ORF | 1125 bp |
| Locus ID | 50796 |
| UniProt ID | Q9QZ59 |
| Gene Summary | Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG225528 | Dmrt1 (tGFP-tagged) - Mouse doublesex and mab-3 related transcription factor 1 (Dmrt1), (10ug) |
CNY 3,140.00 |
|
| MR225528 | Dmrt1 (Myc-DDK-tagged) - Mouse doublesex and mab-3 related transcription factor 1 (Dmrt1) |
CNY 3,656.00 |
|
| MR225528L3 | Lenti ORF clone of Dmrt1 (Myc-DDK-tagged) - Mouse doublesex and mab-3 related transcription factor 1 (Dmrt1) |
CNY 4,750.00 |
|
| MR225528L4 | Lenti ORF clone of Dmrt1 (mGFP-tagged) - Mouse doublesex and mab-3 related transcription factor 1 (Dmrt1) |
CNY 4,750.00 |
