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Pstpip1 (NM_011193) Mouse Untagged Clone
CAT＃: MC209249
Pstpip1 (untagged) - Mouse proline-serine-threonine phosphatase-interacting protein 1 (Pstpip1), (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD2BP1; def-2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC209249 representing NM_011193
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGATGGCCCAGCTGCAGTTCCGAGATGCCTTCTGGTGCAGGGACTTCACGGCCCACACAGGGTATGAGG TGCTACTGCAGAGGCTGCTGGACGGCAGGAAGATGTGCAAGGATGTGGAGGAGCTGCTCAGACAGAGGGC CCAGGCGGAGGAGAGGTACGGGAAGGAGCTGGTGCAGATTGCACGCAAGGCTGGTGGCCAGACAGAGATG AATTCCCTGAGGACCTCCTTTGACTCCCTGAAGCAGCAAACAGAGAATGTGGGCAGTGCACACATCCAGC TGGCCCTGGCCCTGCGTGAGGAGCTGCGGAGCCTGGAGGAGTTCCGAGAGAGACAGAAAGAGCAGCGGAA GAAGTATGAGGCCATCATGGACCGTGTCCAGAAGAGCAAGTTGTCGCTCTACAAGAAGACCATGGAGTCC AAGAAGGCATATGACCAGAAGTGCAGGGATGCAGATGATGCTGAGCAGGCCTTCGAGCGTGTGAGTGCCA ATGGCCACCAGAAGCAAGTAGAAAAGAGCCAGAACAAAGCCAAGCAGTGCAAGGAGTCAGCCACAGAGGC AGAAAGAGTGTACAGGCAAAATATCGAACAACTGGAGAGAGCGAGGACCGAGTGGGAGCAGGAGCACCGG ACTACCTGTGAGGCCTTCCAGTTGCAGGAGTTTGACCGGCTCACCATCCTCCGCAATGCCCTGTGGGTGC ACTGTAACCAGCTCTCCATGCAGTGTGTCAAGGATGATGAGCTCTATGAGGAAGTGCGGCTGACCCTTGA GGGCTGTGATGTGGAAGGTGACATCAATGGCTTCATCCAGTCCAAGAGCACTGGCAGAGAGCCCCCAGCT CCGGTGCCTTATCAGAACTACTATGACAGGGAGGTGACCCCACTGATTGGCAGCCCTAGCGTCCAGCCCT CCTGTGGTGTGATAAAGAGGTTCTCTGGGCTGCTACATGGAAGTCCCAAGACCACACCTTCTGCTCCTGC TGCTTCCACAGAGACTCTGACTCCCACCCCTGAGCGGAATGAGTTGGTCTACGCATCCATCGAAGTGCAG GCGACCCAGGGAAACCTTAACTCATCAGCCCAGGACTACCGGGCACTCTACGACTACACCGCACAGAATT CTGATGAGCTGGACATTTCCGCGGGAGACATCCTGGCGGTCATCCTGGAAGGGGAGGATGGCTGGTGGAC TGTGGAGCGGAACGGACAACGTGGCTTTGTCCCTGGGTCGTACTTGGAGAAGCTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_011193 |
| Insert Size | 1248 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_011193.2, NP_035323.2 |
| RefSeq Size | 1853 bp |
| RefSeq ORF | 1248 bp |
| Locus ID | 19200 |
| UniProt ID | P97814 |
| Gene Summary | Involved in regulation of the actin cytoskeleton. May regulate WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS and allow PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymerization required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through the coupling of PTPN12 to CD2. Also has a role in innate immunity and the inflammatory response. Recruited to inflammasomes by MEFV. Induces formation of pyroptosomes, large supramolecular structures composed of oligomerized PYCARD dimers which form prior to inflammatory apoptosis. Binding to MEFV allows MEFV to bind to PYCARD and facilitates pyroptosome formation. Regulates endocytosis and cell migration in neutrophils.[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG217594 | Pstpip1 (tGFP-tagged) - Mouse proline-serine-threonine phosphatase-interacting protein 1 (Pstpip1), (10ug) |
CNY 3,710.00 |
|
| MR217594 | Pstpip1 (Myc-DDK-tagged) - Mouse proline-serine-threonine phosphatase-interacting protein 1 (Pstpip1) |
CNY 3,330.00 |
|
| MR217594L3 | Lenti ORF clone of Pstpip1 (Myc-DDK-tagged) - Mouse proline-serine-threonine phosphatase-interacting protein 1 (Pstpip1) |
CNY 5,230.00 |
|
| MR217594L4 | Lenti ORF clone of Pstpip1 (mGFP-tagged) - Mouse proline-serine-threonine phosphatase-interacting protein 1 (Pstpip1) |
CNY 5,230.00 |
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