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Pik3r2 (NM_008841) Mouse Untagged Clone
CAT＃: MC205622
Pik3r2 (untagged) - Mouse phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2), (10ug)
CNY 5,296.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | p85beta |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC006796
CGGACGCGTGGGCGCGGCGACGGTGGCTGACGCAGGGATCCCGCGGCTGCGGCGACGGCGGCGGCGGTCG TGGTGGTGGCGACGGCGGCCGGAGTGGGCTGGTGTCCCCGGCTGAGCATGGTAGCAGCCTGTGGTCTGGG TCCCTTCGTCTGGTGTCAGGCACATCTTGAAGAGCCAGTAAGCCTGGGCACCCACAGCCCAGCTAATGAA GGAGTGATCCACCTATCCCAGCTTGACCATCTGATGGGTGACACAAGCCAAATAATTTGAGAAAACACCA GGAACATCATTGCACAGGTGACTAAATGGTGGCCTCTGTGACAGATGGCCATCTAGGCATGTGCGGCCCC CGAGGTCGCCTGTGACTTCTGGAAGTAGAGGTCTACAAGCCCACCACACAGGCCGCACCAGCCCATGGGG TCCCTAGAGCCCCGGGGAGCCAGCTGACGGTCCAGAACCCCCCAGGCCAGCCATGGCAGGAGCCGAGGGC TTCCAGTACAGGGCTGTGTACCCATTCCGCCGGGAGCGGCCTGAAGACCTGGAGCTGCTCCCTGGGGACC TCCTGGTGGTGAGCCGGGTGGCCCTACAGGCACTTGGTGTGGCTGATGGAGGAGAGCGCTGCCCACACAA TGTGGGCTGGATGCCTGGCTTCAACGAGCGCACCCGACAGCGAGGGGACTTCCCCGGGACATACGTGGAG TTCCTAGGACCCGTGGCTCTGGCTCGACCAGGCCCTCGCCCACGGGGGCCCCGTCCGTTGCCCGCCAGGC CCTTGGATGGATCTTCTGAGTCAGGCCACATACTCCCAGACCTGGCAGAGCAGTTCTCCCCACCTGACCC TGCTCCCCCGATTCTGGTGAAGCTGGTGGAAGCCATTGAGCAAGCAGAGCTGGACAGTGAATGCTACAGT AAGCCGGAGCTGCCCGCAACACGGACAGACTGGTCCCTGAGTGACTTGGAGCAGTGGGACCGCACCGCCT TGTATGATGCTGTTAAGGGCTTCCTGCTGGCGTTGCCTGCAGCTGTGGTGACCCCTGAAGCTGCAGCAGA GGCGTACCGGGCACTTCGAGAGGTTGCAGGCCCCGTGGGGCTGGTGCTGGAACCCCCAACACTGCCGCTG CACCAGGCTCTCACACTGCGTTTCCTGCTGCAACACCTGGGTCGCGTGGCCCGCAGAGCACCCTCGCCAG ATACAGCTGTCCATGCACTGGCCAGTGCCTTCGGGCCGCTACTGCTGCGCATACCTCCGTCAGGGGGCGA GGGTGATGGGAGTGAGCCTGTACCCGACTTCCCTGTGCTGCTGCTAGAGAGGCTGGTGCAGGAGCATGTG GAGGAGCAAGACGCTGCCCCCCCAGCGCTACCACCTAAGCCCTCTAAGGCAAAGCCGGCACCCACAGCTC TGGCCAATGGAGGGAGCCCGCCCTCGCTTCAGGATGCAGAGTGGTACTGGGGGGACATCTCCAGGGAAGA GGTGAATGAGAGACTCCGGGACACACCTGATGGTACCTTCTTAGTCAGAGATGCATCCAGCAAGATCCAA GGAGAGTACACGCTCACCCTCAGGAAAGGCGGGAACAACAAGTTGATCAAAGTCTTCCACCGGGATGGTC ACTATGGCTTCTCAGAGCCCCTTACCTTCTGCTCCGTGGTGGAACTCATCTCCCACTACCGCCACGAATC ACTGGCCCAGTACAACGCCAAGCTGGACACACGCCTTCTCTACCCTGTGTCCAAGTACCAACAAGACCAG GTGGTGAAGGAGGACAGCGTAGAGGCTGTGGGCGCCCAGCTCAAGGTCTACCACCAGCAGTACCAGGACA AGAGCCGCGAATATGACCAGCTGTATGAAGAATACACACGGACCTCCCAGGAGCTGCAGATGAAGCGCAC AGCCATAGAGGCCTTCAACGAGACCATCAAGATCTTCGAAGAGCAGGGCCAGACACAGGAGAAGTGCAGC AAGGAGTATTTGGAGCGCTTCCGGCGAGAGGGAAATGAGAAGGAGATGCAGAGGATCCTGCTGAACTCCG AGCGACTCAAGTCTCGCATCGCGGAGATACACGAAAGCCGCACGAAGTTGGAGCAGGATCTGCGGGCGCA GGCCTCCGACAACCGTGAGATCGACAAGCGCATGAACAGCCTCAAACCTGACCTCATGCAGCTGCGCAAG ATCAGGGACCAGTACCTCGTGTGGCTCACCCAGAAAGGTGCCCGACAGAGGAAGATCAACGAATGGCTGG GAATCAAGAACGAGACTGAGGACCAGTATTCACTGATGGAGGATGAGGACGCCCTCCCCCACCACGAGGA GCGCACGTGGTACGTGGGCAAGATCAACCGCACACAGGCGGAGGAGATGCTGAGTGGCAAACGAGACGGG ACCTTCCTCATCCGGGAGAGCAGCCAGCGGGGCTGTTACGCATGCTCCGTGGTGGTGGACGGCGACACGA AGCACTGTGTCATCTACCGCACAGCCACCGGCTTCGGCTTCGCAGAGCCCTATAACCTGTACGGGTCCCT GAAGGAGCTGGTGCTGCACTACCAGCACGCATCACTCGTGCAGCACAATGACGCACTTACCGTCACCCTC GCACACCCTGTGCGTGCCCCCGGGCCTGGCCCACCGTCTGCAGCACGCTGAGCGCCCACCTCGCCTGCCT CCCTGTCCATGTCTGTCTCCAGATCCCCTCCCCTGGTGAACACGCGCAGGAGGCCATCCCTCCCGCTGCG CCTGCCATGTTTACAGAGGCTGTGGGGCCACTGGCCTGGGCGCCCTGAGTTCTTCAAGCCATATACCCGG GGTTAGAAAGGAACCGCGCTAGGTGGTTTCCAGGAACTCAGGCCTGGACACTCGGGGCCGGGCGGGACCC GCCCCGCGGACCCCAACTTCCCCTCTTAAGGTCGAAGTGAAACCAGTCACAGGGGGTTACCCCGCAGCTG CAGAGAATCTTCCCCACTCTGGCGGGCAAAATACAAACTCTGGCCCTCGCCCAGGCCCTGCGCTGTTCTC CAGACTGTGCAATCTCCTCCCCTTTGGGACAAGGGCCCTGGGTGTGTCCCTGCTCCCTGGACCCCATACC TGCCCAGGGTGGATGGGCAGCAGGTTTTGTACGGTACATTTATTGATACGAATATGAAACATTGTACCTG TTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_008841 |
| Insert Size | 2169 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC006796, AAH06796 |
| RefSeq Size | 3194 bp |
| RefSeq ORF | 2169 bp |
| Locus ID | 18709 |
| UniProt ID | O08908 |
| Gene Summary | Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy (By similarity). Promotes nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348926).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210283 | Pik3r2 (tGFP-tagged) - Mouse phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2) |
CNY 7,030.00 |
|
| MR210283 | Pik3r2 (Myc-DDK-tagged) - Mouse phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2) |
CNY 5,288.00 |
|
| MR210283L3 | Lenti ORF clone of Pik3r2 (Myc-DDK-tagged) - Mouse phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2) |
CNY 8,270.00 |
|
| MR210283L4 | Lenti ORF clone of Pik3r2 (mGFP-tagged) - Mouse phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (Pik3r2) |
CNY 8,270.00 |
