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Lat (NM_010689) Mouse Untagged Clone
CAT＃: MC200797
Lat (untagged) - Mouse linker for activation of T cells (Lat), (10ug)
CNY 2,400.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | p36-38; pp36 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC013337 sequence for NM_010689
CCACGCGTCCGCGGACGCGTGGGCGGGGATCGTGCAGCTGGTAGCTGGGGCACGGGCCCCAGCTCTGGCT CTGGGGCGAGCACCTTTCCAGAGCCAACACTGCTCTCAACTCAGTCCAGCAAGAGAGGGGAGCCATCCAG CCCCGAAAGGATACGGCTGCCTACTGCCGGGCGGATCCCAGGCTGGAGCCCGCTTGGTCCCATACCCCTG CTGCCACTCTGTCTCGAGGGGCTGCAGTGCAGCAGGGCCTGTGGCAGGTGCTCTGCAGATGGAAGCAGAC GCCTTGAGCCCGGTGGGGCTGGGCCTCCTGCTGCTGCCCTTCTTGGTCACGCTCCTGGCTGCCCTGTGCG TGCGCTGCCGTGAGTTGCCAGTCTCCTATGACAGCACTTCCACAGAGAGTTTGTACCCAAGAAGCATCCT CATCAAGCCACCTCAAATAACCGTCCCCCGAACACCTGCTGTTTCCTACCCTCTAGTCACTTCCTTCCCA CCCCTGAGGCAGCCAGACCTGCTCCCCATCCCGAGATCCCCACAGCCCCTTGGGGGTTCCCATCGGATGC CATCTTCCCAGCAGAATTCAGATGATGCCAACAGTGTGGCAAGCTACGAGAACCAGGAGCCAGCCTGTAA GAATGTGGATGCAGATGAGGATGAAGACGACTATCCCAACGGCTACCTAGTGGTGCTGCCTGACAGTAGT CCTGCTGCCGTCCCTGTTGTCTCCTCTGCTCCTGTGCCTAGCAACCCTGACCTTGGAGACAGTGCCTTCT CTGTGGAGTCGTGTGAAGATTACGTGAATGTTCCTGAGAGTGAGGAGAGCGCAGAGGCGTCTCTGGATGG GAGCCGGGAGTATGTGAATGTGTCCCCAGAGCAGCAGCCAGTGACCAGGGCTGAGCTGGCCTCTGTGAAC TCCCAGGAGGTGGAAGACGAAGGAGAAGAGGAAGGGGTGGATGGAGAGGAAGCTCCCGACTATGAGAATC TACAGGAGCTTAACTGAAAGCCTACTGCAGCTGTCTGTCCTGAAACTGGACTTGCTGGGGTGTCGCTAAG AGGATCCCATTTGATCTCTGCCTTGCCACAGCCTGAGAATCTTCCCCTAACTTATTGTCACTTTGGGGTC CAGTCTGTGTCCCCAATATTCTGTACCTTCTGATAAAGCCTGAGAATGAATCTGGTTCCAGCCAGACCAT GTCATGGAATAAAGGCCATGTGACATAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_010689 |
| Insert Size | 729 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC013337, AAH13337 |
| RefSeq Size | 1232 bp |
| RefSeq ORF | 729 bp |
| Locus ID | 16797 |
| UniProt ID | O54957 |
| Gene Summary | Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG202998 | Lat (tGFP-tagged) - Mouse linker for activation of T cells (Lat) |
CNY 2,850.00 |
|
| MR202998 | Lat (Myc-DDK-tagged) - Mouse linker for activation of T cells (Lat) |
CNY 2,400.00 |
|
| MR202998L3 | Lenti ORF clone of Lat (Myc-DDK-tagged) - Mouse linker for activation of T cells (Lat) |
CNY 4,750.00 |
|
| MR202998L4 | Lenti ORF clone of Lat (mGFP-tagged) - Mouse linker for activation of T cells (Lat) |
CNY 4,750.00 |
