Lat (NM_010689) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR202998L3V
- LentiORF®
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Lenti ORF particles, Lat (Myc-DDK-tagged) - Mouse linker for activation of T cells (Lat), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Lat (NM_010689) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | p36-38; pp36 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_010689 |
ORF Size | 729 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR202998).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_010689.2, NP_034819.1 |
RefSeq Size | 1260 bp |
RefSeq ORF | 729 bp |
Locus ID | 16797 |
Gene Summary | Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.[UniProtKB/Swiss-Prot Function] |
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