Proteasome subunit alpha type 6 (PSMA6) Mouse Monoclonal Antibody [Clone ID: UMAB102]

Specifications

Product Data
Clone Name	UMAB102
Applications	IHC, WB
Recommend Dilution	IHC 1:100, IF 1:100
Reactivity	Human, Mouse, Rat, Monkey, Dog
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PSMA6 (NP_002782) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5~1.0 mg/ml (Lot Dependent)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	27.2 kDa
Gene Name	proteasome 20S subunit alpha 6
Database Link	NP_002782 Entrez Gene 26443 MouseEntrez Gene 29673 RatEntrez Gene 480290 DogEntrez Gene 695113 MonkeyEntrez Gene 5687 Human UniProt ID P60900
Background	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Jul 2008]
Synonyms	IOTA; p27K; PROS27
Reference Data
Protein Families	Druggable Genome, Protease, Stem cell - Pluripotency
Protein Pathways	Proteasome

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