GRP78 (HSPA5) Mouse Monoclonal Antibody [Clone ID: OTI13C2]

CAT#: TA815945S

HSPA5 mouse monoclonal antibody,clone OTI13C2

Size: 30 ul 100 ul



Need it in bulk or conjugated?
Get a free quote

【特别福利】购一抗正装产品(≥50ul或≥50ug),免费领10ul抗体试用装

CNY 870.00


货期*
现货

规格
    • 30 ul

Product images

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5), 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5)
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Clone Name OTI13C2
Applications WB
Recommend Dilution WB 1:500
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment of Human HSPA5 (NP_005338) produced in Ecoli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Predicted Protein Size 72.3 kDa
Gene Name heat shock protein family A (Hsp70) member 5
Background The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. This protein localizes to the lumen of the endoplasmic reticulum (ER) where it operates as a typical HSP70 chaperone involved in the folding and assembly of proteins in the ER and is a master regulator of ER homeostasis. During cellular stress, as during viral infection or tumorogenesis, this protein interacts with the transmembrane stress sensor proteins PERK (protein kinase R-like endoplasmic reticulum kinase), IRE1 (inositol-requiring kinase 1), and ATF6 (activating transcription factor 6) where it acts as a repressor of the unfolded protein response (UPR) and also plays a role in cellular apoptosis and senescence. Elevated expression and atypical translocation of this protein to the cell surface has been reported in viral infections and some types of cancer cells. At the cell surface this protein may facilitate viral attachment and entry to host cells. This gene is a therapeutic target for the treatment of coronavirus diseases and chemoresistant cancers. [provided by RefSeq, Jul 2020]
Synonyms BIP; GRP78; HEL-S-89n
Reference Data
Protein Families Druggable Genome
Protein Pathways Antigen processing and presentation, Prion diseases
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...