Estrogen Related Receptor alpha (ESRRA) Mouse Monoclonal Antibody [Clone ID: OTI2H9]

Specifications

Product Data
Clone Name	OTI2H9
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 206-417 of human ESRRA (NP_004442) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46 kDa
Gene Name	estrogen related receptor alpha
Database Link	NP_004442 Entrez Gene 2101 Human UniProt ID P11474
Background	The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]
Synonyms	ERR1; ERRa; ERRalpha; ESRL1; NR3B1
Reference Data
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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