Angiopoietin 2 (ANGPT2) Mouse Monoclonal Antibody [Clone ID: OTI4A3]

Specifications

Product Data
Clone Name	OTI4A3
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 19-496 of human ANGPT2(NP_001138) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	54.9 kDa
Gene Name	angiopoietin 2
Database Link	NP_001138 Entrez Gene 11601 MouseEntrez Gene 89805 RatEntrez Gene 285 Human UniProt ID O15123
Background	The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms	AGPT2; ANG2; LMPHM10
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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