Angiopoietin 2 (ANGPT2) Mouse Monoclonal Antibody [Clone ID: OTI4A3]

Specifications

Product Data
Clone Name	OTI4A3
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 19-496 of human ANGPT2(NP_001138) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	54.9 kDa
Gene Name	angiopoietin 2
Database Link	NP_001138 Entrez Gene 11601 MouseEntrez Gene 89805 RatEntrez Gene 285 Human UniProt ID O15123
Background	The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms	AGPT2; ANG2; LMPHM10
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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