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Constitutive androstane receptor (NR1I3) Mouse Monoclonal Antibody [Clone ID: OTI10B1]
CAT＃: TA805313
NR1I3 mouse monoclonal antibody, clone OTI10B1 (formerly 10B1)
Size: 30 ul
Formulation: Carrier-Free
View other "OTI10B1" antibodies (4)
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CNY 1,999.00
CNY 2,700.00
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CNY 300.00
CNY 1,430.00
CNY 3,080.00
CNY 3,080.00
Specifications
| Product Data | |
| Clone Name | OTI10B1 |
| Applications | IHC |
| Recommend Dilution | IHC 1:150 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-236 of human NR1I3 (NP_001070950) produced in E.coli. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 40.3 kDa |
| Gene Name | nuclear receptor subfamily 1 group I member 3 |
| Database Link | |
| Background | This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Synonyms | CAR; CAR1; MB67 |
| Reference Data | |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| CF805313 | Carrier-free (BSA/glycerol-free) NR1I3 mouse monoclonal antibody, clone OTI10B1 (formerly 10B1) |
CNY 3,999.00 |
|
| TA805313AM | NR1I3 mouse monoclonal antibody, clone OTI10B1 (formerly 10B1), Biotinylated |
CNY 3,990.00 |
|
| TA805313BM | NR1I3 mouse monoclonal antibody, clone OTI10B1 (formerly 10B1), HRP conjugated |
CNY 3,990.00 |
|
| TA805313S | NR1I3 mouse monoclonal antibody, clone OTI10B1 (formerly 10B1) |
CNY 800.00 |
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