Isocitrate dehydrogenase (IDH1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1D1]
CAT#: TA800427BM
IDH1 mouse monoclonal antibody,clone 1D1, HRP conjugated
Conjugation: Unconjugated Biotin
View other "OTI1D1" antibodies (4)
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CNY 3,990.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Clone Name | OTI1D1 |
Applications | IHC, WB |
Recommend Dilution | WB 1:500, IHC 1:150 |
Reactivity | Human, Dog, Rat, Monkey, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Synthetic peptide around the R132 region of the human IDH conjugated to KLH |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 46.5 kDa |
Gene Name | isocitrate dehydrogenase (NADP(+)) 1, cytosolic |
Database Link | |
Background | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [provided by RefSeq, Jul 2008] |
Synonyms | HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; PICD |
Reference Data | |
Protein Pathways | Citrate cycle (TCA cycle), Glutathione metabolism, Metabolic pathways |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF800427 | Carrier-free (BSA/glycerol-free) IDH1 mouse monoclonal antibody, clone OTI1D1 (formerly 1D1) |
CNY 3,999.00 |
|
TA800427 | IDH1 (Isocitrate Dehydrogenase 1) mouse monoclonal antibody, clone OTI1D1 (formerly 1D1) |
CNY 1,999.00 |
|
TA800427AM | IDH1 mouse monoclonal antibody,clone 1D1, Biotinylated |
CNY 3,990.00 |
|
TA800427S | IDH1 (Isocitrate Dehydrogenase 1) mouse monoclonal antibody, clone OTI1D1 (formerly 1D1) |
CNY 800.00 |
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