Mannan Binding Lectin (MBL2) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1A12]

Specifications

Product Data
Clone Name	OTI1A12
Applications	IF, IHC, WB
Recommend Dilution	WB 1:4000, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MBL2(NP_000233) produced in HEK293T cell.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	24 kDa
Gene Name	mannose binding lectin 2
Database Link	NP_000233 Entrez Gene 4153 Human UniProt ID P11226
Background	This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]
Synonyms	COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Complement and coagulation cascades

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