Mannan Binding Lectin (MBL2) Mouse Monoclonal Antibody [Clone ID: OTI1A12]

Specifications

Product Data
Clone Name	OTI1A12
Applications	IF, IHC, WB
Recommend Dilution	WB 1:4000, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MBL2(NP_000233) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	24 kDa
Gene Name	mannose binding lectin 2
Database Link	NP_000233 Entrez Gene 4153 Human UniProt ID P11226
Background	This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]
Synonyms	COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Complement and coagulation cascades

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