alpha smooth muscle Actin (ACTA2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A 10aa synthetic peptide corresponding to N-term of human Actin protein. This sequence is identical in human, mouse, rat, bovine and chicken.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	~42 kDa
Gene Name	actin, alpha 2, smooth muscle, aorta
Database Link	NP_001135417 Entrez Gene 11475 MouseEntrez Gene 81633 RatEntrez Gene 59 Human UniProt ID P62736
Background	The Actin protein, a component of the eukaryotic cytoskeleton, is highly conserved between multiple species. It is involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. The levels of the Actin protein may vary between different cell types, but are consistent within a given cell type, and for this reason, Actin protein levels are considered an internal control for protein loading.
Synonyms	AAT6; ACTSA; MYMY5
Reference Data
Protein Pathways	Vascular smooth muscle contraction

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