NIRF (UHRF2) Rabbit Polyclonal Antibody
CAT#: TA351439S
Rabbit Polyclonal Anti-UHRF2 Antibody
Size: 100 ul
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CN¥ 800.00
CN¥ 1,280.00
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CN¥ 6,650.00
CN¥ 4,840.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 50-200 Positive control: Human cervical cancer Predicted cell location: Nucleus |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human UHRF2 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | ubiquitin like with PHD and ring finger domains 2 |
Database Link | |
Background | This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. |
Synonyms | NIRF; RNF107; TDRD23; URF2 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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