KDM4C Rabbit Polyclonal Antibody
CAT#: TA351311S
Rabbit Polyclonal Anti-KDM4C Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 500-2000 WB positive control: Mouse heart and brain tissue |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human KDM4C |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 120 kDa |
Gene Name | lysine demethylase 4C |
Database Link | |
Background | This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. |
Synonyms | GASC1; JHDM3C; JMJD2C; TDRD14C |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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