NUMB Rabbit Polyclonal Antibody
CAT#: TA350244S
Rabbit Polyclonal Anti-NUMB Antibody
Size: 100 ul
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CNY 1,280.00
CNY 300.00
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CNY 2,900.00
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 200-1000 WB positive control: K562, hela, skov3, NIH/3T3 and Raji cells, human testis tissue |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human NUMB |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 71 kDa |
Gene Name | NUMB, endocytic adaptor protein |
Database Link | |
Background | The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. |
Synonyms | C14orf41; c14_5527; S171 |
Reference Data | |
Protein Pathways | Notch signaling pathway |
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