Cofilin 1 (CFL1) Rabbit Polyclonal Antibody

CAT#: TA349816

Rabbit Polyclonal Anti-CFL1 Antibody



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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Recombinant protein of human cofilin 1 (non-muscle) (CFL1), 20 µg
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Specifications

Product Data
Applications WB
Recommend Dilution WB: 500-2000
WB positive control: Raji cells
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein of human CFL1
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 19 kDa
Gene Name cofilin 1
Background The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Synonyms CFL; HEL-S-15
Reference Data
Protein Families Druggable Genome
Protein Pathways Axon guidance, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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