beta Arrestin 1 (ARRB1) Rabbit Polyclonal Antibody

CAT#: TA332389

Rabbit anti-ARRB1 Polyclonal Antibody



Need it in bulk or conjugated?
Get a free quote

热销推荐

CNY 1,999.00

CNY 2,700.00


货期*
2周

规格
    • 100 ul

Product images

经常一起买 (5)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Purified recombinant protein of Homo sapiens arrestin, beta 1 (ARRB1), transcript variant 2, 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of arrestin, beta 1 (ARRB1), transcript variant 1
    • 100 ug

CNY 3,080.00


Purified recombinant protein of Homo sapiens arrestin, beta 1 (ARRB1), transcript variant 2, 100 µg
    • 100 ug

CNY 9,998.00


Transient overexpression lysate of arrestin, beta 1 (ARRB1), transcript variant 2
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Applications ICC/IF, IHC, IP, WB
Recommend Dilution WB 1:500 - 1:2000;IF 1:20- 1:100
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human ARRB1
Formulation PBS with 0.05% proclin300,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 418
Gene Name arrestin beta 1
Background Arrestin proteins function as negative regulators of G protein-coupled receptor (GPCR) signaling. Cognate ligand binding stimulates GPCR phosphorylation, which is followed by binding of arrestin to the phosphorylated GPCR and the eventual internalization of the receptor and desensitization of GPCR signaling (1). Four distinct mammalian arrestin proteins are known. Arrestin 1 (also known as S-arrestin) and arrestin 4 (X-arrestin) are localized to retinal rods and cones, respectively. Arrestin 2 (also known as β-arrestin 1) and arrestin 3 (β-arrestin 2) are ubiquitously expressed and bind to most GPCRs (2). β-arrestins function as adaptor and scaffold proteins and play important roles in other processes, such as recruiting c-Src family proteins to GPCRs in Erk activation pathways (3,4). β-arrestins are also involved in some receptor tyrosine kinase signaling pathways (5-8). Additional evidence suggests that β-arrestins translocate to the nucleus and help regulate transcription by binding transcriptional cofactors (9,10).
Synonyms ARB1; ARR1
Reference Data
Protein Families Druggable Genome
Protein Pathways Chemokine signaling pathway, Endocytosis, MAPK signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...