SOX2 Rabbit Polyclonal Antibody [Clone ID: Poly6308]

Specifications

Product Data
Clone Name	Poly6308
Applications	WB
Recommend Dilution	WB, IF
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide-KLH (N-terminal)
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 50% glycerol.
Purification	The antibody was purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34 kD
Gene Name	SRY-box 2
Database Link	NP_003097 Entrez Gene 6657 Human UniProt ID P48431
Background	This rabbit polyclonal antibody recognizes human SOX2 also known as SRY (sex determining region Y)-box 2 and ANOP3. SOX2 is a nucleus protein, predicted molecular weight 34 kD. SOX2 belongs to the SOX (SRY-box containing gene) gene family which encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate. Defects in SOX2 are a cause of true or primary anophthalmos, also called anophthalmia or ANOP3. Anophthalmos is a developmental defect characterized by complete absence of the eyes (rare) or by the presence of vestigial eyes. The poly6308 antibody has been shown to be useful for Western blotting.
Synonyms	ANOP3; MCOPS3
Reference Data
Protein Families	Adult stem cells, Cancer stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors

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