Macrophage Scavenger Receptor I (MSR1) Rabbit Polyclonal Antibody

CAT#: TA327214

MSR1 Rabbit Polyclonal Antibody



Need it in bulk or conjugated?
Get a free quote

热销推荐

CNY 1,999.00

CNY 2,700.00


货期*
2周

规格
    • 100 ul

Product images

经常一起买 (5)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human macrophage scavenger receptor 1 (MSR1), transcript variant SR-AII, 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of macrophage scavenger receptor 1 (MSR1), transcript variant SR-AIII
    • 100 ug

CNY 3,080.00


Recombinant protein of human macrophage scavenger receptor 1 (MSR1), transcript variant SR-AII, 100 µg
    • 100 ug

CNY 9,998.00


Transient overexpression lysate of macrophage scavenger receptor 1 (MSR1), transcript variant SR-AII
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Applications ICC/IF, WB
Recommend Dilution WB 1:500 - 1:2000
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human MSR1
Formulation PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 50 kDa
Gene Name macrophage scavenger receptor 1
Background This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimers disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008]
Synonyms CD204; phSR1; phSR2; SCARA1; SR-A; SRA
Reference Data
Protein Families Druggable Genome, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

其它Macrophage Scavenger Receptor I产品

Customer Reviews 
Loading...