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gamma Actin (ACTG1) Rabbit Polyclonal Antibody
CAT＃: TA324134S
Anti-ACTG1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Human lymphoma tissue |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 4-379 amino acids of human actin, gamma 1 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 42 kDa |
| Gene Name | actin gamma 1 |
| Database Link | |
| Background | Actins are highly conserved proteins that are involved in various types of cell motility; and maintenance of the cytoskeleton. In vertebrates; three main groups of actin isoforms; alpha; beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton; and as mediators of internal cell motility. Actin; gamma 1; encoded by this gene; is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26; a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants. |
| Synonyms | ACT; ACTG; BRWS2; DFNA20; DFNA26; HEL-176 |
| Reference Data | |
| Protein Pathways | Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Tight junction, Vibrio cholerae infection, Viral myocarditis |
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