PARK7 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Hela and Jurkat cell IHC: 50-200 Positive control: Human lung cancer Predicted cell location: Cytoplasm,Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full length fusion protein
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	20 kDa
Gene Name	Parkinsonism associated deglycase
Database Link	NP_001116849 Entrez Gene 57320 MouseEntrez Gene 117287 RatEntrez Gene 11315 Human UniProt ID Q99497
Background	The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone; as a sensor for oxidative stress; and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Synonyms	DJ-1; DJ1; HEL-S-67p
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Parkinson's disease

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