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GAS 6 (GAS6) Rabbit Polyclonal Antibody
CAT＃: TA323563S
Anti-GAS6 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 5-20 Positive control: Human cervical cancer Predicted cell location: Cytoplasm |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 690-705 amino acids of Human growth arrest-specific 6 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | growth arrest specific 6 |
| Database Link | |
| Background | This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation; and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Ligand for tyrosine-protein kinase receptors AXL; TYRO3 and MER whose signaling is implicated in cell growth and survival; cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis; optimal cytokine signaling during human natural killer cell development; hepatic regeneration; gonadotropin-releasing hormone neuron survival and migration; platelet activation; or regulation of thrombotic responses. |
| Synonyms | AXLLG; AXSF |
| Reference Data | |
| Protein Families | Druggable Genome, Secreted Protein |
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