TRIM32 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Lovo cells IHC: 15-50 Positive control: Human cervical cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 300 amino acids of human tripartite motif containing 32
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	72 kDa
Gene Name	tripartite motif containing 32
Database Link	NP_001093149 Entrez Gene 69807 MouseEntrez Gene 22954 Human UniProt ID Q13049
Background	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains; a RING; a B-box type 1 and a B-box type 2; and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus; where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.
Synonyms	BBS11; HT2A; LGMD2H; TATIP
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Ubiquitin mediated proteolysis

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