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Claudin 7 (CLDN7) Rabbit Polyclonal Antibody
CAT＃: TA323192S
Anti-CLDN7 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 1000-3000 WB positive control: Human liver cancer tissue IHC: 50-150 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Cell membrane |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 199-212 amino acids of Human claudin 7 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 23 kDa |
| Gene Name | claudin 7 |
| Database Link | |
| Background | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets; and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies; including breast cancer; ovarian cancer; hepatocellular carcinomas; urinary tumors; prostate cancer; lung cancer; head and neck cancers; thyroid carcinomas; etc.. Alternatively spliced transcript variants encoding different isoforms have been found. |
| Synonyms | CEPTRL2; claudin-1; CLDN-7; CPETRL2; Hs.84359 |
| Reference Data | |
| Protein Families | Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction |
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