Claudin 7 (CLDN7) Rabbit Polyclonal Antibody

CAT#: TA323192S

Anti-CLDN7 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

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Transient overexpression lysate of claudin 7 (CLDN7)
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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 1000-3000
WB positive control: Human liver cancer tissue
IHC: 50-150
Positive control: Human colon cancer
Predicted cell location: Cytoplasm, Cell membrane
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 199-212 amino acids of Human claudin 7
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 23 kDa
Gene Name claudin 7
Background This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets; and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies; including breast cancer; ovarian cancer; hepatocellular carcinomas; urinary tumors; prostate cancer; lung cancer; head and neck cancers; thyroid carcinomas; etc.. Alternatively spliced transcript variants encoding different isoforms have been found.
Synonyms CEPTRL2; claudin-1; CLDN-7; CPETRL2; Hs.84359
Reference Data
Protein Families Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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