MSH3 Rabbit Polyclonal Antibody

CAT#: TA323011S

Anti-MSH3 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

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经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

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Transient overexpression lysate of mutS homolog 3 (E. coli) (MSH3)
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 25-100
Positive control: Human colon cancer
Predicted cell location: Cytoplasm, Nucleus
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to a C terminal 300 amino acids of human mutS homolog 3 (E. coli)
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name mutS homolog 3
Background The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta; part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.
Synonyms DUP; FAP4; MRP1
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Colorectal cancer, Mismatch repair, Pathways in cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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