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CDC6 Rabbit Polyclonal Antibody
CAT＃: TA321316S
Anti-CDC6 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 200-1000 WB positive control: K562 cells IHC: 25-100 Positive control: Human lung cancer Predicted cell location: Cytoplasm or Nucleus |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 18-32 amino acids of human cell division cycle 6 homolog (S. cerevisiae) |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 63 kDa |
| Gene Name | cell division cycle 6 |
| Database Link | |
| Background | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6; a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1; but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. |
| Synonyms | CDC18L; HsCDC6; HsCDC18 |
| Reference Data | |
| Protein Pathways | Cell cycle |
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