CD59 Rabbit Polyclonal Antibody

CAT#: TA319628

Rabbit Polyclonal CD59 Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

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经常一起买 (5)
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    • 100 ug

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1 - 2 ug/mL
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Rabbit polyclonal CD59 antibody was raised against a 14 amino acid peptide near the amino terminus of human CD59.
Formulation CD59 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification CD59 Antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 14 kDa
Gene Name CD59 molecule
Background CD59 Antibody: The complement regulatory protein CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis and is involved in lymphocyte signal transduction. CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and ultimately cerebral infarction.
Synonyms 1F5; 16.3A5; EJ16; EJ30; EL32; G344; HRF-20; HRF20; MAC-IP; MACIF; MEM43; MIC11; MIN1; MIN2
Reference Data
Protein Families Druggable Genome
Protein Pathways Complement and coagulation cascades, Hematopoietic cell lineage
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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