RAE1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ICC/IF:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Mouse, Rat, Zebrafish, Xenopus, Pig, Bovine, X. tropicalis
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region within amino acids 307 and 368 of RAE1 (Uniprot ID#P78406)
Formulation	1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	41 kDa
Gene Name	ribonucleic acid export 1
Database Link	NP_001015885 Entrez Gene 66679 MouseEntrez Gene 362281 RatEntrez Gene 8480 Human UniProt ID P78406
Background	Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Synonyms	dJ481F12.3; dJ800J21.1; MIG14; Mnrp41; MRNP41
Note	Seq homology of immunogen across species: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Pig (100%), Bovine (100%)
Reference Data

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