REA Rabbit Polyclonal Antibody
CAT#: TA300151
Rabbit Polyclonal Antibody against PHB2
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CNY 6,160.00
货期*
5周
规格
经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 1:1000, IHC: 1:10~50 |
Reactivity | Mouse, Rat, Bovine, Human, Chicken |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | This REA (PHB2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human REA (PHB2). |
Formulation | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration | lot specific |
Purification | This antibody is purified through a protein G column, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Database Link | |
Background | PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging. |
Synonyms | BAP; Bap37; BCAP37; p22; PNAS-141; REA |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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