CD33 Mouse Monoclonal Antibody [Clone ID: HIM3-4]

CAT#: SM3084B

CD33 mouse monoclonal antibody, clone HIM3-4, Biotin

Conjugation: Unconjugated Biotin



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CNY 3,810.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name HIM3-4
Applications FC
Recommend Dilution Indirect Immunofluorescence analysis by Flow Cytometry (1/1000).
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen NFMY-9s Human cell line.
Specificity The antibody HIM3-4 reacts with CD33, a 67 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells; it is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
HLDA V; WS Code M MA112.
HLDA VI; WS Code M MA47.
Formulation PBS, pH~7.4
Label: Biotin
State: Liquid purified Ig fraction
Preservative: 15 mM Sodium Azide
Label: -LC-NHS, The reagent is free of unconjugated Biotin.
Concentration lot specific
Purification Affinity Chromatography
Conjugation Biotin
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name CD33 molecule
Background CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.
Synonyms Siglec-3, gp67
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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